@article{ajmbr2018614,
author={{Boyvin, Lydie and Zokor¨¦, Zazou Ange Kevin and Ak¨¦, Aya Jeanne Armande and N¡¯Guessan, Yao Nestor and S¨¦ri, Kipr¨¦ Laurent and Yapo, Adou Francis and Djaman, Allico Joseph},
title={Importance of Measuring Serum C-peptide in the Biological Care of Hyperglycemia Patients and Diabetics¡¯ Patients on Insulin in C?te d¡¯Ivoire},
journal={American Journal of Medical and Biological Research},
volume={6},
number={1},
pages={16--20},
year={2018},
url={http://pubs.sciepub.com/ajmbr/6/1/4},
issn={2328-4099},
abstract={Diabetes, the leading cause of high blood glucose, is a pandemic disease with serious complications (paralyzing, deadly) despite the available diabetes treatment. C -Peptide, is generally secreted in amounts equal to insulin in the blood, is a reliable marker of insulin function and production in diabetics patients under insulin therapy. In C?te d¡¯Ivoire, the prevalence of diabetes is 2.3% (2015) and no study has been conducted so far on the C-peptide to evaluate the actual proportion of insulin in high blood glucose. This is a prospective study based on cases-controls conducted on a cohort of 60 patients and 30 controls from the period of November 2015 to February 2016 .The study involved only adult patients¡¯ with hyperglycemia blood samples on one hand and those assumed diabetics on insulin therapy. Pregnant women and children were not included. Analysis of C-peptide was performed on the sera from blood samples collected. Using ELISA kit chain PR 4100 by Bio-rad. The results show that the mean value of the C- peptide is normal with no significant difference in patients with hyperglycemia (P = 0.1343). However, the difference is significant in diabetics patients on insulin therapy (p < 0.0001). In conclusion, the determination of C-peptide level allowed knowing the amount of insulin secreted by the pancreas. It would be better, with the persistence situation of hyperglycemia, to evaluate the concentration level of C-peptide before commencement of any diabetes treatment exogenous insulin in particular.},
doi={10.12691/ajmbr-6-1-4}
publisher={Science and Education Publishing}
}