@article{ajmbr2015351,
author={{Ojekale, Anthony B. and Lawal, Oladipupo A. and Jewo, Peter I. and Oguntola, Jamiu. A. and Abdul, Latifat O.},
title={<i>Cissus populnea </i>(Guill &amp; Perr): A Study of the Aqueous Extract as Potential Spermatogenic Enhancers in Male Wistar Rats},
journal={American Journal of Medical and Biological Research},
volume={3},
number={5},
pages={124--127},
year={2015},
url={http://pubs.sciepub.com/ajmbr/3/5/1},
issn={2328-4099},
abstract={<b>Background</b>: There is a global observed decline in male fertility over the years consequent on various factors affecting spermatogenesis. Some Nigerian males across various geographic and socio-economic strata employ the use of herbals such as <i>Cissus populnea</i> extracts amongst others to manage this and also as herbal aphrodisiacs. This study assessed the spermatogenic effects of aqueous extract of <i>Cissus populnea</i> stem bark. <b>Methodology</b>: <i>Cissus populnea</i> stem bark was extracted with water, concentrated and lyophilized. Male wistar rats were orally administered with 150 mg/kg body weight of aqueous extract (<i>Cissus populnea</i>) over a 64 day period. Sperm of the experimental animals was collected, and the parameters (count, motility, morphology) analysed. Data were analysed with SPSS 19. <b>Principal findings</b>: The oral administration of <i>C. populnea </i>extract over a 64 day period to male wistar rats resulted in a four-fold increase in sperm count in the test rats (145¡À55) compared with the control group (44¡À17). Testicular histology shows better packed spermatozoa in group of rats treated with <i>Cissus populnea</i>. <b>Conclusion/significance</b>: The findings suggest that oral administration of <i>Cissus populnea </i>aqueous extract improves spermatogenesis in male wistar rats.},
doi={10.12691/ajmbr-3-5-1}
publisher={Science and Education Publishing}
}