eng Science and Education Publishing American Journal of Medical and Biological Research 2328-4099 2014-12-22 2 6 121 123 10.12691/ajmbr-2-6-1 AJMBR2014261 article Sabitha Kandi 1 Sudhakar T 1 C Ramadevi 2 B Venugopal 2 R Rajkumar 2 Md Rafi 2 K V Ramana tejaswani19@gmail.com 3 Department of Biochemistry, Chalmeda AnandRao Institute of Medical Sciences, Bommakal, Karimnagar, Andhra Pradesh Department of Obsterics and Gynaecology, Chalmeda AnandRao Institute of Medical Sciences, Bommakal, Karimnagar, Andhra Pradesh Department of Microbiology, Prathima institute of Medical Sciences, Nagnur, Karimnagar, Andhra Pradesh Preeclampsia is an idiopathic multisystem disorder specific to pregnancy and development of hypertension and proteinuria, increased vascular resistance and endothelial dysfunction in the mother , altered placental perfusion and restricted fetal growth. The vasospasm leads to destruction of RBCs release iron thus, there is elevated serum iron levels in preeclamptic women. The excess iron released from destruction of RBCs can react with free radicals produced from cell membrane (as it is rich in polyunsaturated fatty acids) and circulating lipoproteins initiates lipid peroxidation both in placenta and vasculature. This is one of the significant etiologic factors in the endothelial cell damage of preeclampsia. the raised serum iron levels in turn alters the iron related parameters like total iron binding capacity(TIBC), serum ferritin, transferrin, percent saturation. http://pubs.sciepub.com/ajmbr/2/6/1/ajmbr-2-6-1.pdf preeclampsia serum iron levels TIBC transferrin