eng Science and Education Publishing American Journal of Medical and Biological Research 2328-4099 2014-10-19 2 4 97 100 10.12691/ajmbr-2-4-3 AJMBR2014243 article K V Ramana ramana_20021@rediffmail.com 1 Venkata BharatKumar Pinnelli 2 Sabitha Kandi 3 Asha G 3 Jayashankar CA 4 Bhanuprakash 5 Raghavendra DS 5 Sanjeev D rao 5 Department of Microbiology, Prathima Institute of Medical sciences, Karimnagar, India Department of Biochemistry, Vydehi Institute of Medical sciences and Research center, Bengaluru, India Department of Biochemistry, Chalmeda Anandarao Institute of Medical sciences, Karimnagar, India Department of General Medicine, Vydehi Institute of Medical sciences and Research center, Bengaluru, India Department of Dermatology, Vydehi Institute of Medical sciences and Research center, Bengaluru, India Sepsis is a potential clinical condition which is a consequence of infectious disease or a severe inflammatory reaction secondary to infection or injury. Sepsis in Greek means putrefaction or decay, correlating well with the multiple organ failure and severe shock resulting in death of the patient suffering from severe sepsis. Clinical management of sepsis requires prompt laboratory diagnosis and formulation of effective patient management strategies that may include antimicrobial chemotherapy in case of sepsis induced by infectious microbe. Although many laboratory biomarkers are available for the diagnosis of sepsis, only few markers have proven to be beneficial in differentiating infectious disease sepsis and sepsis of non-infectious origin. Of the available markers only few have prognostic value. We in this review discuss the utility of a novel and emerging sepsis marker, the presepsin which has a better diagnostic and prognostic value, and has been effective in predicting the survival of the sepsis patients. http://pubs.sciepub.com/ajmbr/2/4/3/ajmbr-2-4-3.pdf presepsin sepsis marker management of sepsis