eng Science and Education Publishing American Journal of Medical and Biological Research 2328-4099 2014-08-19 2 4 87 90 10.12691/ajmbr-2-4-1 AJMBR2014241 article T Sudhakar 1 Sabitha Kandi 2 B venugopal 2 K. Bhagwan Reddy 3 K. V. Ramana ramana_20021@rediffmail.com 3 Department of Biochemistry, HOD lab in-charge, Apollo Reach Hospital, Karimnagar, Andhra Pradesh Department of Biochemistry, Chalmeda Anadrao Institute of Medical Sciences, Karimnagar Department of Biochemistry, Prathima Institute of Medical Sciences, Karimnagar The parathyroid gland secretes parathyroid hormone (PTH) which is a key element in the regulation of serum calcium. The PTH elevates serum calcium activities by regulating its action on the bones, kidneys and small intestine. The set point of PTH secretion defines the sensitivity of the parathyroid glands to calcium concentration. Secondary hyperparathyroidism (SHPT) is a common complication of end stage renal disease (ESRD). Ionized calcium is physiologically active form of calcium status of the body and is used for accurately monitoring calcium status in renal diseases. The present study states that the ionized calcium is the set point of secondary hyperparathyroidism undergoing haemodialysis and the range of set point lies between 2.3 - 4.8 mg/dl (0.57 - 1.2 mmol/L). The status of iPTH, set point are frequently monitored in subtotal hyperparathyroidectomy where imaging studies are not beneficial (anatomically situated on postero-lateral surface of thyroid gland) to know the appearance of parathyroid gland. http://pubs.sciepub.com/ajmbr/2/4/1/ajmbr-2-4-1.pdf set point ionized calcium Secondary hyperparathyroidism (SHPT) haemodialysis