eng Science and Education Publishing American Journal of Infectious Diseases and Microbiology 2328-4064 2020-09-03 8 3 95 98 10.12691/ajidm-8-3-2 AJIDM2020832 article Eno Etim Nyong 1 Enobong E. Ikpeme 1 Sunday Babatunde Adesina adesinasunday08@gmail.com 1 Department of Paediatrics, University of Uyo Teaching Hospital, Uyo, Nigeria Background: Timely and effective antimicrobial therapy is important in the management of urinary tract infection in the new born. An accurately tailored empirical therapy, informed by periodic documentation of the aetiological agents through urine culture and antimicrobial sensitivity pattern determination is imperative in achieving this goal. This will reduce potential morbidities of delay, and ensure effective therapy before the arrival of urine culture results. The organisms causing neonatal UTI in the University of Uyo Teaching Hospital Uyo, Nigeria and their antimicrobial sensitivity pattern have not been documented in research. Objective: To determine the implicated aetiological agents of Neonatal Urinary tract infection(UTI) in the University of Uyo Teaching Hospital and their antimicrobial sensitivity pattern. Methods: A cross-sectional study on all neonates diagnosed as `suspected sepsis` who underwent sepsis evaluation between December 2013 and September 2015. Urine specimens were collected by clean catch urine collection method for culture. Results: Escherichia coli was the commonest organism isolated. Others were Klebsiella pneumonia, Morganella species and Staphylococcus aureus. Conclusions Escherichia coli was the commonest organism which was sensitive to some of the third generation Cephalosporins such as Ceftazidime and Cefotaxime.Sensitivities to Ceftriaxone, Cefuroxime and Gentamicin which initially were routine in the management of neonatal infections in the facility was comparably low. http://pubs.sciepub.com/ajidm/8/3/2/ajidm-8-3-2.pdf neonatal neonate urinary tract infection