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<records>
  <record>
    <language>eng</language>
    <publisher>Science and Education Publishing</publisher>
    <journalTitle>American Journal of Infectious Diseases and Microbiology</journalTitle>
    <eissn>2328-4064</eissn>
    <publicationDate>2020-01-30</publicationDate>
    <volume>8</volume>
    <issue>1</issue>
    <startPage>20</startPage>
    <endPage>23</endPage>
    <doi>10.12691/ajidm-8-1-3</doi>
    <publisherRecordId>AJIDM2020813</publisherRecordId>
    <documentType>article</documentType>
    <title language="eng">Opportunistic Infections in Patients Living with HIV at Brazzaville University Hospital: Prevalence and Associated Factors</title>
    <authors>
      <author>
        <name>Ossibi Ibara BR</name>
        <email>ossibiibara@gmail.com</email>
        <affiliationId>1</affiliationId>
        <affiliationId>2</affiliationId>
      </author>
      <author>
        <name>Bemba ELP</name>
        <affiliationId>2</affiliationId>
        <affiliationId>3</affiliationId>
      </author>
      <author>
        <name>Okemba Okombi FH</name>
        <affiliationId>3</affiliationId>
        <affiliationId>3</affiliationId>
      </author>
      <author>
        <name>Mouloungui M</name>
        <affiliationId>3</affiliationId>
      </author>
      <author>
        <name>Adoua Doukaga T</name>
        <affiliationId>3</affiliationId>
        <affiliationId>3</affiliationId>
      </author>
      <author>
        <name>Angonga Pabota E</name>
        <affiliationId>3</affiliationId>
      </author>
      <author>
        <name>Ekat M</name>
        <affiliationId>3</affiliationId>
      </author>
      <author>
        <name>Ellenga-Mbolla BF</name>
        <affiliationId>3</affiliationId>
        <affiliationId>4</affiliationId>
      </author>
    </authors>
    <affiliationsList>
      <affiliationName affiliationId="1">Faculty of Health Sciences, Marien NGOUABI University, Brazzaville-Congo</affiliationName>
    </affiliationsList>
    <abstract language="eng">Objectives: To determine the prevalence of opportunistic infections in the Infectious Diseases Department and to look for associated factors. Patients and Methods: A descriptive and analytical retrospective study of patients living with HIV, diagnosed in pre- or per-hospitalization, receiving or not receiving highly active antiretroviral therapy, in which an opportunistic infection related to AIDS has been documented. Results: A total of 548 patients included (22.7% of admissions) of average age of 39.9±11.2 years (17-82 years), mostly female (n-339; 61.9%), singles (n-403;73.5%), with a primary education level (n-218;39.8%). The majority (n=403; 73,5%) came from an urban area, with a primary education level (n-218;39.8%), residing in cities (n-403;73).77 Patients working in the informal sector were overwhelmingly represented (n-357;65.1) followed by the unemployed (n-51; 9.3%). The average consultation time was 29 ±3.5 (6-42) days. Type 1 HIV was the most found (419; 78.1%) and Lower CD4&lt; 200/mm3 in 93 patients. The most common opportunistic infections found were Tuberculosis (n-231;42.2%), Toxoplasmosis (n-85;15.5%) and Neuromeningeal Cryptococcosis (n-58; 10.6%). Only 381 patients were on ARTV (69.5%), first-line (n-124; 74.3%). The average length of hospital stay was 20.4-11.8 (5-60) days. The overall lethality was 68%. Conclusion: Opportunistic infections remain common at the Brazzaville University Hospital in an HIV-depressed population1. Tuberculosis affects lethality, which is high as a result of therapeutic non-compliance. This is to say the importance of early HIV testing and management to minimize the emergence of opportunistic diseases in this area.</abstract>
    <fullTextUrl format="pdf">http://pubs.sciepub.com/ajidm/8/1/3/ajidm-8-1-3.pdf</fullTextUrl>
    <keywords language="eng">
      <keyword>opportunist</keyword>
      <keyword>HIV</keyword>
      <keyword>prevalence</keyword>
      <keyword>associated factors</keyword>
      <keyword>CHU</keyword>
      <keyword>Brazzaville</keyword>
    </keywords>
  </record>
</records>