@article{ajidm2018621,
author={{Kariuki, Waititu Kenneth and Nyerere, Kimang¡¯a Andrew and Samuel, Kariuki and Apondi, Obiero Jael},
title={Antimicrobial Susceptibility Patterns of <i>Escherichia coli</i> Isolated from Olive Baboon (<i>Papio anubis</i>) Gut},
journal={American Journal of Infectious Diseases and Microbiology},
volume={6},
number={2},
pages={38--45},
year={2018},
url={http://pubs.sciepub.com/ajidm/6/2/1},
issn={2328-4064},
abstract={<b>Background</b>: Antimicrobial resistance is widely acknowledged as a global health problem that has resulted in devastating emerging and re-emerging conditions which are difficult to manage due to limited or unavailable intervention options. It is deepened by the fact that genes encoding for antimicrobial resistance can be transferred horizontally by mobile genetic elements. <i>Escherichia coli</i> is primarily a gut microbial flora in warm-blooded animals including non-human primates that can acquire any of these gene elements from other resistant bacterial strains resulting in their transmission between humans and animals. This study aimed to determine antimicrobial susceptibility of <i>E. coli</i> against commonly used agents as well as production of extended spectrum ¦Â-lactamases. <b>Methods</b>: <i>E. coli </i>was isolated from stool samples that were collected from sixty-two captive and sixty-two wild baboons using culture-based methods. The isolates were subjected to fourteen antimicrobial agents followed by characterization of three putative resistance genes; <i>bla</i><SUB>CTX-M</SUB>, <i>bla</i><SUB>TEM</SUB> and <i>bla</i><SUB>SHV</SUB> using polymerase chain reaction. <b>Results</b>: <i>E. coli</i> isolates from both groups of animals were resistant to all antimicrobial agents except Ciprofloxacin. Prevalence of Ampicillin resistance was high in <i>E. coli</i> isolated from both captive (32.3%) and wild (35.5%) baboons. There was higher prevalence of ESBLs in <i>E. coli</i> isolated from wild (17.7%) than captive (14.5%) baboons. <b>Conclusion</b>: As reservoirs of ESBL producing <i>E. coli</i> type<i>, </i>baboons could play a potential role in antibiotic resistant plasmids transmission to the environment and other animals including humans.},
doi={10.12691/ajidm-6-2-1}
publisher={Science and Education Publishing}
}