@article{ajidm2016414,
author={{Kurhade, Arvind M. and Mishra, Meena and Kurhade, Geeta and Vaillant, Angel Justiz and Lakhdive, Sudhir and Kurhade, Krutika and Joshi, Tejaswini H. and Vuma, Sehlule},
title={Keratomycosis: Some Epidemiological Data, Diagnosis and Drug Sensitivity},
journal={American Journal of Infectious Diseases and Microbiology},
volume={4},
number={1},
pages={22--24},
year={2016},
url={http://pubs.sciepub.com/ajidm/4/1/4},
issn={2328-4064},
abstract={<b>Purpose:</b> The present study was undertaken to investigate the prevalence of mycotic keratitis and the profile of the fungi responsible in this region. Special attention was given to assess the prevalence of various species of <i>Aspergillus</i>, predisposing factors for keratomycosis and drug sensitivity. <b>Methods:</b> Corneal scraping samples from 148 cases of corneal ulcer and traumatic corneal infection with clinically suspicion of having fungal infections were examined microscopically and for culture. Minimum inhibitory concentration (MIC) of itraconazole and amphotericin-B were tested against the <i>Aspergillus </i>species isolates. <b>Result</b><b>s</b><b>:</b> <i>Aspergillus</i> species were isolated in 26 (20.15%) cases and <i>Aspergillus fumigatus</i> was the predominant species isolated in 17 (65.38%) cases. This fungus was found to be sensitive to itraconazole with MIC of 0,125 -1 ¦Ìg/ml. <b>Conclusion:</b> <i>Aspergillus fumigatus</i> is more common in mycotic keratitis, and itraconazole is effective against it. Vegetative trauma is the major risk factor.},
doi={10.12691/ajidm-4-1-4}
publisher={Science and Education Publishing}
}