Science and Education Publishing American Journal of Infectious Diseases and Microbiology 1 1 2013 05 10 Photodynamic Disinfection of Dentures 34 37 EN Angelina Pecheva Vlahova Department of Prosthetic Dental Medicine, Faculty of Dental Medicine, Plovdiv, Bulgaria Christo Kalchev Kissov Elka Vakrilova Popova Georgi Rangelov Todorov AJIDM2013122 10.12691/ajidm-1-2-2 2012 12 28 2013 05 05 2013 05 10 Photodynamic disinfection is a new method for cleaning dentures of edentulous patients. It is based on the photochemical action of a photoactive dye (photosensitizer), activated by proper light in the presence of oxygen. The mechanism of photosensitization directs the generation of reactive oxygen species that destroy the pathogens. A pilot study of photodynamic disinfection of dentures was carried out. Four different photosensitizers susceptible to red light were used for the investigation. Results showed that photodynamic disinfection is an effective method for inactivation of pathogens on dentures as a part of prevention of cross-contamination in dental office. It also can be used as a part of the therapy of denture stomatitis.