eng Science and Education Publishing American Journal of Food Science and Technology 2333-4835 2020-10-28 8 6 226 232 10.12691/ajfst-8-6-1 AJFST2020861 article Abdoulaye Thiam athiam747@yahoo.fr 1 2 Momar Talla Gueye 2 Cheikhna Hamala Sanghare 2 2 El Hadji Barka Ndiaye 2 2 Serigne Mback¨¦ Diop 2 2 Papa Seyni Cissokho 2 Michel Bakar Diop 3 Ibrahima Ndiaye 3 Marie-Laure Fauconnier 4 Laboratoire des Analyses Phytosanitaires, Institut de Technologie Alimentaire, BP 2765 Hann-Dakar, S¨¦n¨¦gal UFR des Sciences Agronomiques, d¡¯Aquaculture et de Technologie Alimentaire (S2ATA), Universit¨¦ Gaston Berger BP 234 Saint Louis, S¨¦n¨¦gal Chimie G¨¦n¨¦rale et Organique, D¨¦partement Agro-Bio-Chem, Gembloux Agro-Bio Tech, Universit¨¦ de Li¨¨ge 2, Passage des D¨¦port¨¦s-5030 Gembloux, Belgique Apium graveolens var. dulce commonly known as celery, belongs to the Apiaceae family. It is used especially as a vegetable and medicinal plant. In Senegal, A. graveolens is used as a food condiment. The aim of this work is to study the chemical composition of A. graveolens stems (S), leaves (L) essential oils and anti-inflammatory activity. GC/FID and GC/MS analyzes carried out on essential oils obtained by steam distillation showed that oils from both stems and leaves were characterized by the same major constituents ¦Á-pinene, the prominent compound of oils represented 69.3 and 68.4% for stems (S) and leaves (L), respectively. It is followed by limonene (9.5 and 9.8%), ¦Á-phellandrene (5.5 and 5.9%) and ¦Â-pinene (4.8 and 4.3%). These compounds represented 89.1% (S) and 88.4% (L) of the total essential oils content. Anti-inflammatory activity was measured by the inhibition of 5-lipoxygenase (5-LOX) by A. graveolens essential oil anti-inflammatory assays revealed an IC50 of 29.5±2.0 µg/mL for A. graveolens oils and 23.7±0.5 µg/mL for quercetine used as a reference. This study showed that essential oils of A. graveolens was an important source of ¦Á-pinene who is probably responsible of its anti-inflammatory properties. http://pubs.sciepub.com/ajfst/8/6/1/ajfst-8-6-1.pdf Apium graveolens essential oils ¦Á-pinene linoleic acid 5-lipoxygenase and anti-inflammatory