eng Science and Education Publishing American Journal of Food and Nutrition 2374-1163 2019-08-01 7 3 72 77 10.12691/ajfn-7-3-1 AJFN2019731 article Md. Taslim Hossain 1 Md. Nazibur Rahman 2 Md. Mukter Hossain mukter.vetmed@sau.ac.bd 3 Youth Training Center, Department of Youth Development, Ministry of Youth and Sports, Bangladesh Department of Biochemistry and Molecularbiology, Jahangirnagar University, Savar, Dhaka, Bangladesh Department of Medicine, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet 3100, Bangladesh In this study, 100 clinically diagnosed types 2 diabetic patients were selected for investigation. The objective of this study was to control of blood glucose level in type 2 diabetic patient by the modification of conventional diet composition. The patients were studied using a randomized 5 week crossover design with the conventional and modified conventional diet (test diet) respectively. The mean body weight, BMI, waist circumference and waist to hip ratio were 60.1 ± 2.21 kg, 24.1 ± 2.71 kg/meter², 36.2 ± 0.762 inch and 0.904 ± 0.029 respectively with the conventional diet, that decreased to 59.5 ± 2.20 kg (P<0.01), 23.9 ± 2.73 kg/ meter² (P<0.05), 33.7 ± 0.512 inch (P<0.05) and 0.897 ± 0.026 (P<0.05) respectively after intervention of the test diet. The mean systolic and diastolic blood pressure were 124 ± 11.4 and 82 ± 6.9 mmHg respectively and after 5 weeks of intervention of test diet both the blood pressure decreased significantly (P<0.05) to 112 ± 8.6 and 69± 6.9 mmHg respectively. The mean fasting and postprandial blood sugar were 10.4 ± 0.38 and 12 ± 0.53 mmol/l with the conventional diet whereas it decreased significantly (P <0.001) to 8.1 ± 0.75 and 9.8 ± 0.40 mmol/l respectively. Before starting the test diet, the mean HbA1C was 6.4 ± 0.13 % but 5 week of post feeding the HbA1C decreased to 5.8 ± 0.19 % ( P<0.001). The mean ALT value was 47.5 ± 8.95 u/l and decreased significantly (P < 0.05) to 24.5 ± 4.19 u/l. During conventional diet, the mean AST and ALP level were 55.8 ± 25.18 and 93 ± 6.06 u/l respectively, after intervention it decreased to 42.8 ± 27.43 and 75 ± 10.85 u/l but not significantly (P = 0.759, P= 0.337). http://pubs.sciepub.com/ajfn/7/3/1/ajfn-7-3-1.pdf blood glucose conventional diet modification diet type 2 diabetes