Science and Education Publishing American Journal of Epidemiology and Infectious Disease 2 1 2013 12 26 Modelling of HIV-TB Co-infection Transmission Dynamics 1 7 EN Nita H. Shah Department of Mathematics, Gujarat University, Ahmedabad, Gujarat Jyoti Gupta AJEID2014211 10.12691/ajeid-2-1-1 2013 11 26 2013 12 12 2013 12 26 In this paper, we have formulated a model for HIV-TB co-infection using differential equations in order to understand the dynamics of disease spread. The model is analysed for all the parameters responsible for the disease spread in order to find the most sensitive parameters out of all. Steady state conditions are derived. A threshold parameter R0 is defined and is shown that the disease will spread only if its value exceeds 1. Numerical simulation is done for the model using MATLAB which shows the population dynamics in different compartments.