@article{ajeid2013132,
author={{Moses, Alo and Uchenna, Ugah and Nworie, Okoro},
title={Epidemiology of Vancomycin Resistant <i>S</i><i>taphyloccus</i><i> A</i><i>ureus</i> among Clinical Isolates in a Tertiary Hospital in Abakaliki, Nigeria},
journal={American Journal of Epidemiology and Infectious Disease},
volume={1},
number={3},
pages={24--26},
year={2013},
url={http://pubs.sciepub.com/ajeid/1/3/2},
abstract={<i>Staphylococcus aureus </i>is a successful pathogen due to a combination of numerous bacteria immune-evasive strategies. The increased incidence of MRSA has led to more frequent use of vancomycin, the drug commonly relied upon as last resorts for treating MRSA infections. As a consequence, selective pressure was established that led to the emergence of strains of <i>S. aureus </i>and other species of <i>Staphylococci</i> with decreased susceptibility to vancomycin and other glycopeptides. The aim of our study was to determine the prevalence of vancomycin resistant <i>S. aureus </i>among clinical isolates in a tertiary health care facility in Abakaliki metropolis, the capital of Ebonyi State, South Eastern Nigeria. The susceptibility of S. aureus strains to vancomycin was determined by Kirby-Bauer disk diffusion technique as well as by tube dilution method. Among the 355 <i>S. aureus</i> isolates tested, 272 (76.6%) isolates were susceptible (zone diameter ¡Ý 15mm, MIC 0.5-2¦Ìg/ml) 64 (18.0%) isolates were intermediate (zone diameter ¡Ü 14mm, MIC 4-8¦Ìg/ml) while 19 (5.4%) isolates were resistant (zone diameter ¡Ü 14mm, MIC ¡Ý 16¦Ìg/ml). When subjected to statistical analysis, this prevalence rate was statistically non-significant (p &lt; 0.05). But, nevertheless, clinically relevant considering the overall implication in the transfer of resistant gene.},
doi={10.12691/ajeid-1-3-2}
publisher={Science and Education Publishing}
}