@article{ajcp2016414,
author={{Chen, Wei and Yang, Xiaoli and Wu, Yakun},
title={The Effect of Local Regional Therapy on Post-transplantation Survival Rate in Patients with Hepatocellular Carcinoma},
journal={American Journal of Cancer Prevention},
volume={4},
number={1},
pages={18--22},
year={2016},
url={http://pubs.sciepub.com/ajcp/4/1/4},
issn={2328-7314},
abstract={<b>Background</b><b> and </b><b>Objective:</b><b> </b>This study aims to use meta-analysis to evaluate whether pre-transplantation local regional therapy (LRT) can improve the survival of patients with hepatocellular carcinoma who accepted liver transplantation. <b>Methods:</b> Relevant studies were identified by searching PUBMED, EMBASE and Web of Science Datebases up to May 2015. Endpoints were 1 year, 3 years, and 5 years survival rate after liver transplantation. <b>Results:</b> Analysis of nine retrospective studies including 1097 patients did not reveal significant difference in 1year, 3 years and 5 years survival rate between the patients who got LRT or not. Analysis of four retrospective studies including 504 patients showed patients with complete response to LRT have higher 5 years survival rate. <b>Conclusions:</b> The results of this meta-analysis suggest that the patients with complete response to LRT have higher post-transplantation survival rate. But LRT before liver transplantation can¡¯t improve the overall survival rate.},
doi={10.12691/ajcp-4-1-4}
publisher={Science and Education Publishing}
}