@article{ajcp2015357,
author={{Payandeh, Mehrdad and Sadeghi, Masoud and Sadeghi, Edris},
title={The Ki-67 index in non-Hodgkin's Lymphoma: Role and Prognostic Significance},
journal={American Journal of Cancer Prevention},
volume={3},
number={5},
pages={100--102},
year={2015},
url={http://pubs.sciepub.com/ajcp/3/5/7},
issn={2328-7314},
abstract={<b>Background</b>: Ki67 is a nuclear and nuclear protein antigen present in all proliferating cells during the active part of the cell cycle: G1, S, G2, and mitosis. The aim of study is to evaluate survival based on Ki67 index in NHL patients in the west of Iran for the first time. <b>Patients and Methods:</b> Between of 2002 to 2014, fifty-six patients with NHL referred to Our Clinic. We checked age, sex, type of NHL, Ki67 index and survival for them. We divided Ki67 index to two groups: low Ki67 (Ki67&lt;65%) and high Ki67 (Ki67¡Ý65%). <b>Results</b>: The mean age at diagnosis for patients was 47.33¡À166.50 years (range, 13-77 years) that 27 patients (48.2%) had age¡Ü 50 years and 33 patients (58.9%) were male. Thirty-eight patients (67.9%) had Ki67&lt;60% and 18 patients (32.1%) had Ki67¡Ý65%. The mean Ki67 for Nodal patients was 48.1% and for extra nodal was 54.5%, but there was no significant correlation between them (P=0.360). <b>Conclusion</b>: Ki67 in future studies should be divided based on a fix percent until we can have a better result about the role of Ki67 in NHL patients. Also, Ki67 alone can not be a risk factor in NHL patients and other factors such as age, sex and type of NHL can be affective, too.},
doi={10.12691/ajcp-3-5-7}
publisher={Science and Education Publishing}
}