eng Science and Education Publishing American Journal of Cancer Prevention 2328-7314 2015-10-08 3 5 91 93 10.12691/ajcp-3-5-4 AJCP2015354 article Ali Shahriari-Ahmadi 1 Babak Izadi 2 Masoud Sadeghi Sadeghi_mbrc@yahoo.com 3 4 Mehrdad Payandeh 4 Edris Sadeghi 4 4 Rasool-Akram Hospital, Oncology and Hematology ward, Iran University of Medical Sciences, Tehran, Iran Department of Medical Oncology, Kermanshah University of Medical Sciences, Kermanshah, Iran Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran Background: Epstein-Barr virus (EBV) infection is highly associated with specific subtypes of malignant lymphoma such as types of aggressive non-Hodgkin lymphoma (NHL). We aimed to evaluate the prevalence of EBV in NHL and its association with clinical parameters. Patients and Methods: twenty cases entered to our study. After re-blocking of previous paraffin embedded specimens, new slides were prepared and DNA was extracted. DNA contents were confirmed by spectrophotometery. Then PCR assay was used for total DNA and its product evaluate for presence of EBV by electrophoresis. Results: The mean age at diagnosis for all patients was 45±13 years (range, 28-73) years that 12 patients (60%) were male. Based on histopathology reports, 13 patients (65%) had immunoblastic Lymphoma, 5 (25%) had burkitt Lymphoma and 2 (10%) had LL (lymphoblastic Lymphoma). Conclusion: There is no EBV infection in NHL patients with LLs and percent of EBV infection in our study is lower than other studies. http://pubs.sciepub.com/ajcp/3/5/4/ajcp-3-5-4.pdf EBV infection NHL Burkitt lymphoma