Dear Label_Name,

Greetings! I hope you are well.

I am writing on behalf of an international publishing house, Science and Education Publishing, USA (http://www.sciepub.com).

Science and Education Publishing (SciEP) is a multidisciplinary open access publisher of Journals covering the fields of Science, Technology and Medicine. All SciEP publications are subject to high-quality peer review, editorial and production processes and are freely available online.

Welcome to the April, 2013 edition of SciEP newsletter, providing monthly summaries of articles on science & education related topics of interest to scientist and professionals. The mission of our journals is to provide an open access forum for publishing new findings on issues pertinent to scientific and academic field. We also invite you to submit original research papers, review articles, short reports, or case studies are considered for publication in our Multidisciplinary Journals.

American Journal of Public Health Research
DOI: 10.12691/ajphr-1-1-3

The Implementation of a Tele-Homecare System with Service Oriented Architecture and HL7 Message Transmission Standard
Ching-Sung Wang

American Journal of Medical and Biological Research
DOI: 10.12691/ajmbr-1-1-2

The Influence of Ethanol on Pyruvate Kinases Activity in Vivo, in Vitro, in Silico
Lelevich Sergey Vladimirovich, Khrustalev Vladislav Victorovich, Barkovsky Eugene Victorovich, Shedogubova Tatyana Aleksandrovna

American Journal of Medical Sciences and Medicine
DOI: 10.12691/ajmsm-1-1-1

Clinical and Histological Features in Wegener Granulomatosis
Li Cavoli Gioacchino, Passantino Rita, Bono Luisa, Tortorici Calogera, Ferrantelli Angelo, Giammarresi Carlo, Rotolo Ugo

American Journal of Infectious Diseases and Microbiology
DOI: 10.12691/ajidm-1-1-2

The Curse of Lymphatic Filariasis: Would the Continual Use of Diethylcarbamazine Eliminate this Scourge in Papua New Guinea?
Anne Lanham, Lillian Mwanri

We have released issues of some journals on February 2013.
American Journal of Public Health Research
American Journal of Medical Sciences and Medicine
American Journal of Medical and Biological Research
American Journal of Pharmacological Sciences
American Journal of Clinical Medicine Research
American Journal of Nursing Research
American Journal of Cancer Prevention
American Journal of Medicine Studies
American Journal of Infectious Diseases and Microbiology
American Journal of Cardiovascular Disease Research
American Journal of Biomedical Research
American Journal of Mechanical Engineering
American Journal of Microbiological Research
Journal of Preventive Medicine
American Journal of Food and Nutrition
American Journal of Hypertension Research
American Journal of Sports Science and Medicine
Journal of Cancer Research and Treatment
American Journal of Zoological Research
Journal of Biomedical Engineering and Technology
American Journal of Microbiological Research
Biomedical Science and Engineering

We are pleased to announce that submissions are now being accepted for peer review for all the journals across all our subject areas in SciEP.

Please submit your manuscript via our online submission system:
http://www.sciepub.com/author/signin

To unsubscribe from our mailing list, please click on the following link: unsubscribe

I am looking forward to hearing from you.

Kind regards,

David Rain
Email:join@sciepub.com
Science and Education Publishing (http://www.sciepub.com)

Diffuse large B-Cell Non-Hodgkin's of Bronchus-associated Lymphoid Tissue (BALT) Lymphomas: Case Report

Mehrdad Payandeh, Edris Sadeghi*, Masoud Sadeghi, Faezeh Gholami

Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran

Abstract: Introduction: Bronchus-associated Lymphoid Tissue (BALT) lymphomas are a rare type of extranodal marginal zone lymphomas. Herein we report a rare instance, diffuse large B cell type lymphoma can present primarily in the lung. Case Report: A 57-year-old female patient was admitted to our clinic in November 2008, with complaints of shortness of breath, fever and a cough associated with the production of small amounts of phlegm. CT scan showed interstitial infiltration in between inspiratory. Pathological report revealed lymphoproliferative disorder (diffuse large B cell lymphoma) after left lung lobectomy. She was treated with six cycles of chop (cyclophosphamide + doxorubicin + vincristine + prednisolone) chemotherapy. Chest radiographs demonstrated significantly reduced in the parnshymal tissue in both lungs. Conclusion: DLBCL of BALT is very rare with nonspecific signs and symptoms. Furthermore, CHOP chemotherapy may be an effective treatment of the disease.

Keywords: BALT, CHOP chemotherapy, DLBCL

Received May 20, 2015; Revised September 10, 2015; Accepted October 07, 2015

Citation: Mehrdad Payandeh, Edris Sadeghi, Masoud Sadeghi, Faezeh Gholami, Diffuse large B-Cell Non-Hodgkin's of Bronchus-associated Lymphoid Tissue (BALT) Lymphomas: Case Report. American Journal of Cancer Prevention, 3 (5). 84-85. January 2015. doi:10.12691/ajcp-3-5-1

1. Introduction

Bronchus-associated Lymphoid Tissue (BALT) lymphomas are a rare type of extranodal marginal zone lymphomas [1]. Primary malignant lymphoma of the lung may develop from bronchus-associated lymphoid tissue (BALT) [2]. Primary pulmonary diffuse large B-cell lymphoma (DLBCL) is particularly rare and occurs only in 10% cases of primary pulmonary NHL [3]. Herein we report a rare instance, diffuse large B cell type lymphoma can present primarily in the lung.

2. Case Report

A 57-year-old female patient was admitted to our clinic in November 2008, with complaints of shortness of breath, fever and a cough associated with the production of small amounts of phlegm. CT scan showed interstitial infiltration in between inspiratory (Figure 1). Pathological report revealed lymphoproliferative disorder (diffuse large B cell lymphoma) after left lung lobectomy. Percent of Ki67 was 60% of tumor cells and also BCL2, CD45, CD20, CD3 were positive but CD5, CD10, EMA, cytokeratrin, CD30 and CD15 were negative. She was treated with six cycles of chop (cyclophosphamide + doxorubicin + vincristine + prednisolone) chemotherapy. Chest radiographs demonstrated significantly reduced in the parnshymal tissue in both lungs (Figure 2).

Figure 1. Marked interstitial infiltration can be seen

Figure 2. Tumor size was significantly reduced in the parnshymal tissue

3. Discussion

Primary malignant non-Hodgkin’s lymphomas arising in mucosa-associated lymphoid tissue (MALT) develop most frequently in the stomach, but also in the bowel, salivary glands, larynx, thyroid gland, and lung. Accordingly, when located in the lung, this lymphoma appears to arise from bronchus-associated lymphoid tissue (BALT) [2,4]. Methods for the treatment of primary pulmonary DLBCL, including simple monitoring, surgery, chemotherapy and chemotherapy followed by radiotherapy, are controversial and there is no uniform treatment strategy [5]. To the best of our knowledge, patients with primary pulmonary DLBCL have no overt symptoms during the initial stages; however, as the disease progresses, they are likely to present with non‑specific symptoms, including dyspnea, cough, chest pain, sputum and other obstructive and infectious symptoms, as well as fever and weight loss [5]. Previously reported CT features of BALT lymphoma are the presence of consolidation with poorly defined margins and air bronchograms [2]. This indicates that anthracycline-based chemotherapy may be an optimal therapeutic strategy for patients with primary pulmonary DLBCL [6].

4. Conclusion

DLBCL of BALT is very rare with nonspecific signs and symptoms. Furthermore, CHOP chemotherapy may be an effective treatment of the disease.

References

[1]   | Arnaoutakis K, Oo TH. Bronchus-associated lymphoid tissue lymphomas. South Med J. 2009. 102 (12): 1229-33.
[2]   | Lee DK, Im JG, Lee KS, Lee JS, Seo JB, Goo JM, et al. B-cell lymphoma of bronchus-associated lymphoid tissue (BALT): CT features in 10 patients. JComput Assist Tomogr.2000. 24 (1): 30-34.

[3]  
Zinzani PL, Martelli M, Poletti V, Vitolo U, Gobbi PG, Chisesi T, et al. Practice guidelines for the management of extranodal non-Hodgkin's lymphomas of adult non-immunodeficient patients. Part I: primary lung and mediastinal lymphomas. A project of the Italian Society of Hematology, the Italian Society of Experimental Hematology and the Italian Group for Bone Marrow Transplantation. Haematologica. 2008. 93 (9): 1364-71. Epub 2008 Jul 4.

[4]   | O’Donnell PG, Jackson SA, Tung KT, Hassan B, Wilkins B, Mead GM. Radiological appearance of lymphomas arising from mucosa-associated lymphoid tissue (MALT) in the lung. Clin Radiol. 1998. 53 (4): 258-263.
[5]   | Cadranel J, Wislez M and Antoine M: Primary pulmonary lymphoma. Eur Respir J.2002. 20 (3): 750-62.
[6]   | Aviles A, Nambo MJ, Huerta-Guzman J, Silva L, Neri N. Rituximab in the treatment of diffuse large B-cell lymphoma primary of the lung. Hematology. 2013 Mar; 18 (2): 81-4. Epub 2013 Jan 16.