eng Science and Education Publishing American Journal of Clinical Medicine Research 2328-403X 2019-03-08 7 1 31 36 10.12691/ajcmr-7-1-6 AJCMR2019716 article Sudung O. Pardede 1 Putri Maharani Tristanita Marsubrin putristanita2806@yahoo.com 1 Rini Sekartini 1 Zakiudin Munasir 1 Departement of Child Health, Faculty of Medicine, Universitas Indonesia-Cipto Mangunkusumo Hospital, Jakarta, Indonesia Background: Nephrotic syndrome (NS) is a common kidney disease found in children. Its medical and psychosocial complications can affect the quality of life (QoL). The aim of this study was to have a description on the QoL and its related factors using Pediatric Quality of Life InventoryTM (PedsQLTM). Methods: An analytical descriptive study was conducted on patients, aged 2-18 years old in the outpatient and inpatient ward of nephrology, Department of Child Health, Dr. Cipto Mangunkusumo Hospital, Jakarta, during April 2013-December 2013. The assessment of QoL used PedsQLTM 4.0 Chi-square test was performed to get variable with p value <0.25 which subsequently included in multivariate analysis. Logistic regression was performed to find factors associated with QoL. Unpaired t test was performed to find correlation between length of illness and QoL. Results: 100 NS patients were participated in this study and 19% was found having disturbance in the QoL. Risk factors of disturbance in QoL were: age 5-7 years old, age 13-18 years old, low socio-economic status, father with low education level, and the use of steroid (p<0.05). Duration of illness was related to QoL based on parents and children reports (p<0.05), as well as child-rearing pattern. Conclusions: 19% of NS had disturbance in QoL. The risk factors were children age, low socio-economic and low level education of parents, unexpected child-rearing pattern, duration of illness, and the use of steroid. http://pubs.sciepub.com/ajcmr/7/1/6/ajcmr-7-1-6.pdf Nephrotic syndrome QoL PedsQL^TM child-rearing pattern