eng Science and Education Publishing American Journal of Clinical Medicine Research 2328-403X 2015-05-26 3 2 24 30 10.12691/ajcmr-3-2-2 AJCMR2015322 article Dhrubajyoti Bandyopadhyay drdhrubajyoti87@gmail.com 1 Adrija Hajra 2 Sabyasachi Mukhopadhyay 3 Manas Layek 3 Diptak Bhowmick 3 Vijayan Ganeshan 3 Sibnarayan Sasmal 3 Debarati Bhar 3 Cankatikachoudhury 3 Partha Sarathi Karmakar 3 Department of accident and emergency, Lady Hardinge Medical College, New Delhi Department of Internal Medicine, IPGMER, Kolkata Department of Internal Medicine, RG Kar Medical College, Kolkata Background & objectives: Stroke is the one of the important causes of death.Uric acid is described as a strong endogenous antioxidant that is consumed early in acute stroke. Uric acid being an aqueous antioxidant can become a pro-oxidant under certain circumstances, particularly, if other antioxidants such as ascorbate are low. This work was conducted to find an association between serum uric acid levels at the time of admission with functional outcome in patients with acute stroke. Method: This study was carried out on 96 patients of stroke including both ischemic and hemorrhagic stroke. Sampling scheduled one day of the week by rotation to avoid selection bias and the study design was descriptive, observational, cross-sectional study. Result: we found statistically significant positive correlation between serum uric acid level and change in Mathew score in ischemic stroke patients and poor positive correlation between uric acid level and change of Mathew score in hemorrhagic stroke patients. Conclusion: High serum uric acid level is associated with good neurological outcome in patients with acute ischemic stroke. A high serum uric acid level is associated with insignificant poor neurological outcome in patients with hemorrhagic stroke. http://pubs.sciepub.com/ajcmr/3/2/2/ajcmr-3-2-2.pdf acute stroke mathew score Uric acid (UA)