eng Science and Education Publishing American Journal of Cardiovascular Disease Research 2022-08-31 8 1 49 52 10.12691/ajcdr-8-1-5 AJCDR2022815 article K. A. M. Mahbub Hasan mahbub.ripon51@gmail.com 1 M. Atahar Ali 2 Nupur Kar 3 Pradip Kumar Karmakar 3 Md. Abdullah Yusuf 4 Naheed Fatema 5 Department of Cardiology, National Institute of Cardiovascular Diseases, Sher-E-Bangla Nagar, Dhaka, Bangladesh Department of Cardiology, Evercare Hospital Limited, Dhaka, Bangladesh Department of Cardiology, National Institute of Cardiovascular Diseases, Dhaka, Bangladesh Department of Microbiology, National Institute of Neurosciences & Hospital, Dhaka, Bangladesh Department of Obstetrics and Gynecology, Bangladesh Medical College, Dhaka, Bangladesh Background: Echocardiographic epicardial fat thickness may be associated with metabolic syndrome. Objective: The purpose of the present study was to see the association of epicardial fat thickness with metabolic syndrome. Methodology: This comparative cross-sectional study was conducted in the Department of Cardiology at National Institute of Cardiovascular Diseases, Dhaka, Bangladesh from April 2017 to March 2018 for a period of one year. Depending on the diagnosis of metabolic syndrome (MetS), patients were divided into two groups, group I patients with MetS and group II patients without MetS. The epicardial fat thickness of group I and group II were prospectively examined by echocardiography. Then the comparison of the epicardial fat thickness was done between the two groups. Result: A total of 130 patients were included in this study of which 65 patients were assigned in group I and the rest of 65 patients were assigned in group II. The mean age of group I and group II patients were 44.4±9.8 years and 43.7±10.2 years (p = 0.77). The mean epicardial fat thickness (mm) was found significantly higher in patients with metabolic syndrome than in patients without metabolic syndrome which was 5.7 ± 0.83 mm and 2.7 ± 0.86 mm (p=0.001). The analysis had revealed that BMI, LDL, HDL, FBS, WC, age and diagnosis of metabolic syndrome were the independent determinants of increased epicardial fat thickness (p<0.05). Conclusion: In conclusion metabolic syndrome is associated with increased echocardiographic epicardial fat thickness. http://pubs.sciepub.com/ajcdr/8/1/5/ajcdr-8-1-5.pdf association echocardiography epicardial fat thickness metabolic syndrome lipid profiles