eng Science and Education Publishing American Journal of Cardiovascular Disease Research 2021-07-27 7 1 10 12 10.12691/ajcdr-7-1-3 AJCDR2021713 article Sahra Ahmadi Sahra.Ahmadi@wellstar.org 1 Jennifer Giuseffi 2 Department of Internal Medicine, WellStar Kennestone Medical Center, Marietta, GA, United States of America Department of Cardiology, WellStar Kennestone Medical Center, Marietta, GA, United States of America Infective endocarditis (IE) is a life-threatening inflammation of the endocardial surface of the heart usually caused by an infection in a patient with a pre-existing heart condition. Isolated pulmonic valve IE cases without risk factors comprise a very small entity of cases. Bacteremic speciation with a coagulase-negative staphylococci, although not as common as its coagulase positive counterpart, carries significant pathogenic potential and deserves regard. Staphylococcus lugdunensis commonly lives on a person¡¯s skin that is typically harmless when it remains outside the body but associated with high morbidity and mortality when present in the bloodstream. Our case describes a patient with IE of the pulmonic valve without risk factors cultured with the virulent Staphylococcus lugdunensis. http://pubs.sciepub.com/ajcdr/7/1/3/ajcdr-7-1-3.pdf infective endocarditis staphylococcus lugdunensis pulmonic valve native valve