@article{ajbr2021923,
author={{Jan, Abdulhalem A. and Aljeraisi, Ahmed M. and Algarni, Abdullah M. and Almozini, Mohammed A. and Alsyed, Nashwa A. and Alharbi, Suliman A. and Tobaiqi, Muhammad A. and Aljabri, Hemaed and Mulla, Nasser M. and Alsayed, Alaa A. and Sayed, Salah Mohamed El},
title={Relationship between COVID-19 Infection and ABO Blood Groups Differences: A Tertiary Centre Experience in Al-Madinah, Saudi Arabia},
journal={American Journal of Biomedical Research},
volume={9},
number={2},
pages={36--42},
year={2021},
url={http://pubs.sciepub.com/ajbr/9/2/3},
issn={2328-3955},
abstract={Controversial factors affecting COVID-19 infection include age, ethnicity, blood groups and Rh factor were investigated here. This study enrolled 2012 participants: COVID-19 cases (1006 patients), and control group (1006 subjects), 50.9% were Saudis and 49.1% were non-Saudis. Mean age for all participants was 36.0¡À12.7 years and ranged from 8 to 80 years. Mean age was 38.6+15.3 years for COVID-19+ve cases and 33.4¡À8.6 years for controls. Mean age significantly differed in COVID-19+ve cases from controls (p<0.001). COVID-19 infection was significant in Saudi participants compared to non-Saudi participants (p<0.001). In COVID-19 group, the frequencies of blood groups O, A, B and AB were 44.5%, 31.3%, 19.7% and 4.5%, respectively. The percentage of COVID-19 infection was higher in subjects having blood groups O and A. Regarding Rh factor, 94.0% of all participants were Rh+ve and 6.0% were Rh-ve. Among COVID+ve cases, 93.4% were Rh positive cases and 6.6% were Rh negative cases, while in the controls, 94.5% were Rh+ve and 5.5% were Rh-ve. The number of COVID-19+ve cases exceeded the number of healthy controls in A+ve subjects but not in O+ve and B+ve subjects. In multivariate analysis, people with blood groups B and AB were less likely to be infected (p =0.049) compared to those with groups O and A. In conclusion, older adults had greater risk of COVID-19 infection. Gatherings culture increased COVID-19 infection. Individuals with blood groups B and AB are less likely to get COVID-19 infection than O and A subjects. Rh+ve in O+ve and A+ve is associated with increased COVID-19 infection.},
doi={10.12691/ajbr-9-2-3}
publisher={Science and Education Publishing}
}