eng Science and Education Publishing Applied Ecology and Environmental Sciences 2328-3920 2018-01-17 6 1 15 22 10.12691/aees-6-1-3 AEES2018613 article C. Laauser 1 G. Habekost 2 A. Habekost A.Habekost@t-online.de 2 Ludwigsburg University of Education, Department of Chemistry, Reuteallee 46, D-71634 Ludwigsburg, Germany University of Hildesheim, Hildesheim, Germany A flow tube reactor containing iron or zinc powder in a nitrogen atmosphere is capable of performing >90% anaerobic reductive dehalogenation of the cancer drugs ifosfamide and cyclophosphamide at 400 °C using toluene, alcohol or water as proton donors and iron or zinc as reducing agents. The products are all chlorine-free, as proven by GC-MS. The process is particularly interesting for large-scale industrial applications. http://pubs.sciepub.com/aees/6/1/3/aees-6-1-3.pdf reductive dehalogenation anti-cancer drugs mass spectrometry