@article{aees20221086,
author={{S, Sugandhi and G, Rani},
title={Anti-cancer Effect of Gold Nanoparticles of <i>Gracilaria</i> sp. against HeLa and MCF-7 Cell Lines},
journal={Applied Ecology and Environmental Sciences},
volume={10},
number={8},
pages={534--539},
year={2022},
url={http://pubs.sciepub.com/aees/10/8/6},
issn={2328-3920},
abstract={The main objective of this study was to examine the anticancer activities of the gold nanoparticles of marine seaweeds <i>viz</i>., <i>Gracilaria verrucosa, G</i>.<i> pudumadamensis </i>and <i>G</i>.<i> salicornia. </i>Gold nanoparticles of the three species of <i>Gracilaria</i> were tested for their anticancer properties <i>in vitro </i>against HeLa and MCF-7 cancer cell lines. HeLa cell line is cervical cancer cells and MCF-7 is breast cancer cells. The anticancer activity of gold nanoparticles of the seaweed was observed based on cell viability and morphology of the treated cells and control. Among the three species, <i>G</i>. <i>verrucosa</i><i> </i>showed a greater activity with an IC 49.80 against HeLa than the other two species. While greater anticancerous activity was observed in <i>G</i>. <i>salicornia</i> with IC 49.69 against MCF-7 cell line.  The morphology of the treated cells showed a great variation when compared to the control cells. Thus, the <i>in vitro </i>assay indicated that the gold nanoparticles synthesized by these red seaweeds are the significant source of a noble anticancer agent. The study also revealed that <i>G</i>.<i> verrucosa, G</i>.<i> pudumadamensis</i><i> </i>and <i>G</i>.<i> </i><i>salicornia</i><i> </i>could be the promising bioagents for cancer therapy in the near future.},
doi={10.12691/aees-10-8-6}
publisher={Science and Education Publishing}
}