@article{aees2013133,
author={{Akinrotimi, O.A. and Gabriel, U.U and Orokotan, O.O.},
title={Changes in Enzymes Activities of <i>Clarias Gariepinus</i> Brood Fish Exposed to Anaesthetics Metomidate},
journal={Applied Ecology and Environmental Sciences},
volume={1},
number={3},
pages={37--40},
year={2013},
url={http://pubs.sciepub.com/aees/1/3/3},
abstract={<i>The effect of anaesthetic metomidate on the enzymes activities (Alanine transminase ¨C ALT; Aspartate transaminase ¨C AST; Alkaline phosphatase-ALP and Lactate dehydrogenase ¨C LDH) in female Clarias gariepinus was investigated using different concentrations (0.00mlL</i><SUP><i>-1</i></SUP><i> ¨C control; 0.25; 0.75; 1.00; 2.00; 6.00; 8.00; 10.00 and 12.00mlL</i><SUP><i>-1</i></SUP><i>) in triplicates. The results from the study indicated that the anaesthetic caused a concentration dependent significant increase (p &lt; 0.05) in the four enzymes under consideration. The highest activities in all the enzymes were observed in 12.00mlL</i><SUP><i>-1</i></SUP><i> and the lowest in the control.</i><i> </i><i>The results from this work therefore suggests that the anaesthetics impair enzymes activities in the fish which was more noticeable in the fish exposed to higher concentration of 8.00-12.00m/L</i><SUP><i>-1</i></SUP><i>.</i><i> </i><i>Hence caution should be exercised in the application of this anaesthetics in sedation of C. gariepinus.</i>},
doi={10.12691/aees-1-3-3}
publisher={Science and Education Publishing}
}