http://www.sciepub.com/portal/Journals Most frequently read articles for Science and Education Publishing http://pubs.sciepub.com/wjac/1/1/1 f value of tolperisone hydrochloride was observed to be 0.50 ± 0.008. The densitometric analysis was carried out in absorbance mode at 261nm. The linear regression analysis data for the calibration plots showed a good linear relationship for tolperisone hydrochloride over a concentration range of 50 - 800 ng/spot. The limit of detection and limit of quantification for tolperisone hydrochloride was found to be 7.57 and 10ng/spot. Tolperisone hydrochloride was subjected to acid and alkali hydrolysis, chemical oxidation, wet hydrolysis, dry heat degradation and sun light degradation. The degraded product peaks were well resolved from the pure drug peak with significant difference in their R_f values. Stressed samples were assayed using developed HPTLC method. The proposed method was validated with respect to linearity, accuracy, precision and robustness. The method was successfully applied to the estimation of tolperisone in tablet dosage forms. The proposed study describes a HPTLC method for the estimation of tolperisone in bulk and their pharmaceutical dosage form. Statistical analysis showed that the method is suitable for the routine analysis of tolperisone in tablets.]]> Usmangani K. Chhalotiya, Kashyap K. Bhatt, Dimal A. Shah, Dhruti C. Nagda, Gautam R. Chauhan 2013-02-28 Science and Education Publishing 2013-02-28 1 1 1 7 10.12691/wjac-1-1-1 http://pubs.sciepub.com/education/1/7/7 Roman Yavich, Alexandra Gerkerova 2013-08-05 Science and Education Publishing 2013-08-05 7 1 260 262 10.12691/education-1-7-7 http://pubs.sciepub.com/materials/1/3/4 P. A. Gavrish 2013-09-02 Science and Education Publishing 2013-09-02 3 1 46 48 10.12691/materials-1-3-4 http://pubs.sciepub.com/tjant/1/1/4 Mehmet Kir, Hükmi Kiziltunc 2013-09-23 Science and Education Publishing 2013-09-23 1 1 13 16 10.12691/tjant-1-1-4 http://pubs.sciepub.com/ijcd/2/2/1 Jarmila Kabátová 2014-03-31 Science and Education Publishing 2014-03-31 2 2 38 39 10.12691/ijcd-2-2-1 http://pubs.sciepub.com/ijp/2/6/3 Radwan M. Kassir 2014-10-28 Science and Education Publishing 2014-10-28 6 2 197 201 10.12691/ijp-2-6-3 http://pubs.sciepub.com/ajme/1/7/26 Peter Frankovský, Darina Hroncová, Ingrid Delyová, Ivan Virgala 2013-11-12 Science and Education Publishing 2013-11-12 7 1 282 288 10.12691/ajme-1-7-26 http://pubs.sciepub.com/plant/1/3/3 A. H. M. Mahbubur Rahman 2013-11-26 Science and Education Publishing 2013-11-26 3 1 62 67 10.12691/plant-1-3-3 http://pubs.sciepub.com/ajmr/1/2/2 M. Saravanan, Anima Nanda, Tewelde Tesfaye 2013-04-03 Science and Education Publishing 2013-04-03 2 1 21 24 10.12691/ajmr-1-2-2