ISSN (Print): 2372-4668

ISSN (Online): 2372-4676


Editor-in-chief: Mehrdad Hamidi, Javad Verdi

Currrent Issue: Volume 3, Number 1, 2015


Study on Biological Synthesis of Cadmium Sulfide Nanoparticles by Bacillus licheniformis and Its Antimicrobial Properties against Food Borne Pathogens

1Department of Biotechnology, Sri Jayachamarajendra College of Engineering, JSS Technical Institutions Campus, Mysuru

Nanoscience and Nanotechnology Research. 2015, 3(1), 6-15
doi: 10.12691/nnr-3-1-2
Copyright © 2015 Science and Education Publishing

Cite this paper:
Aishwarya Shivashankarappa, K R Sanjay. Study on Biological Synthesis of Cadmium Sulfide Nanoparticles by Bacillus licheniformis and Its Antimicrobial Properties against Food Borne Pathogens. Nanoscience and Nanotechnology Research. 2015; 3(1):6-15. doi: 10.12691/nnr-3-1-2.

Correspondence to: K  R Sanjay, Department of Biotechnology, Sri Jayachamarajendra College of Engineering, JSS Technical Institutions Campus, Mysuru. Email:


The green synthesis of cadmium sulfide (CdS) nanoparticles has been regarded as the most promising technique for their prospective applications in biological system. The bacterial strain Bacillus licheniformis has shown to be efficient in synthesizing cadmium sulfide nanoparticles. We report the effect on nanocrystal formation by varying the ratios of cadmium chloride and sodium sulfide ranging from 1:1, 2:1, 3:1 and 4:1 respectively. The resultant CdS nanoparticles was tested for antimicrobial activity against a range of food borne bacteria E coli, Bacillus licheniformis, Pseudomonas aeruginosa, Bacillus cereus and Staphylococcus aureus and fungi Fusarium oxysporum, Aspergillus flavus and Penicillium expansum. The results showed that the CdS nanoparticles were crystalline in nature with size varying from 20-40 nm. The stability of nanoparticles was due to protein interaction which may have played an important role as capping agents. The antimicrobial activity showed that the CdS nanoparticles of ratio 4:1 of cadmium chloride and sodium sulfide at a concentration of 40 mg/ml showed highest zone of inhibition in Psedomonas aeruginosa (26.5±0.70) and Aspergillus flavus (27.8±0.28). The present study explains a simple, cost effective way of nanoparticle synthesis suitable for large scale production. The green synthesis approach extends the horizon of applications to biological systems as an effective medicinal agent.



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Isolation and Characterization of Bionanofibers from Moringa Oleifera Gum as a Platform for Drug Delivery

1Department of Pharmaceutics (PG), Sanjivani College of Pharmaceutical Education and Research, Kopargaon

Nanoscience and Nanotechnology Research. 2015, 3(1), 1-5
doi: 10.12691/nnr-3-1-1
Copyright © 2015 Science and Education Publishing

Cite this paper:
Gitanjali Mehetre, Vishal Pande, Prakash Kendre. Isolation and Characterization of Bionanofibers from Moringa Oleifera Gum as a Platform for Drug Delivery. Nanoscience and Nanotechnology Research. 2015; 3(1):1-5. doi: 10.12691/nnr-3-1-1.

Correspondence to: Vishal  Pande, Department of Pharmaceutics (PG), Sanjivani College of Pharmaceutical Education and Research, Kopargaon. Email:


Bionanofibers were isolated from Moringa Oleifera gum by carrying out combination of acid hydrolysis and probe sonication treatment. Acid hydrolysis of hemicelluloses was carried out to remove amorphous region. An increase in sulphuric acid concentration from 20 to 60 wt% accelerates the breakages in hemicelluloses molecules, leading to narrower, less polydisperse bionanofibers. After sonication, the fibers were cleaved into small fibers with dimensions on the nanoscale. The characterization of bionanofibers was performed by Scanning Electron Microscopy (SEM), Particle size, Differential Scanning Calorimetry (DSC), Fourier transform infrared spectroscopy (FTIR). Surface morphology was observed by SEM which confirms presence of bionanofibers. Bionanofibers having diameter at 98 nm while length of 20 µm. The thermal analysis of Moringa oleifera gum was done by DSC. Fourier transform infrared spectroscopy (FTIR) showed that some breakages of intramolecular hydrogen bonds and glycosidic bonds held during hydrolysis reaction of Moringa Oleifera. The isolated nanofibers can be used in novel drug delivery system as platform to load the desired drug.



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