Special Issue Call for Papers

American Journal of Medical Sciences and Medicine

Special Issue Call for Papers

Special Issue on Anesthesia and Analgesia

General anesthesia and regional anesthesia techniques are used in surgical procedures. Both intra-operative anesthesia and postoperative analgesia are important topics for patient and surgery. Some regional anesthesia techniques provide important advantages compared with general anesthesia for postoperative pain control in some surgical procedures. For example, epidural anesthesia, a regional anesthesia technique, is not only performed for adequate anesthesia in the surgical procedures but also for pain control. There are other advantages for the use of regional anesthesia techniques including excellent pain control, reduced side effects, improved cardiac and pulmonary function, and shortened stay in the post-anesthesia care unit. The use of regional anesthesia is also associated with decreased neuro-endocrine stress responses in the peri-operative period.
Regional anesthesia is one of the important methods for multimodal postoperative pain control. Regional anesthesia would provide excellent pain control and improve outcome such as decrease in side effects, improvement of pulmonary function, prevention of chronic pain, or reduction in hospital stay. Thus the regional anesthetic techniques and outcome using regional anesthesia for postoperative pain have becoming one of the important fields.
We invite authors to submit original research and review articles that seek to define the interaction between anesthesia and postoperative pain control. We are interested in articles that explore aspects of the effect of anesthesia techniques for pain control in humans and also in animal models.

About the issue

The topics of this special issue include, but are not limited to:

  • Regional anesthesia techniques
  • Spinal, epidural and peripheral nevre blocks
  • Local anesthetics and adjuvants for pain control
  • Catheter–based nerve blocks for pain control
  • Ultrasound-guided nevre blocks
  • Patient-controlled analgesia
  • Regional anesthesia and neuroendocrine stress responses
  • Comparison of general and regional anesthesia for pain control

Important dates

Submission Deadline: October 27, 2014
Notification of Acceptance: November 28, 2014
Final Version Due: December 15, 2014
Special Issue Publishing Date: December 29, 2014

Chief Guest Editor

Ahmet Eroglu
Karadeniz Technical University
Email: erogluah@hotmail.com

Guest Editor

Can Ince
Erasmus University Rotterdam
Email: c.ince@erasmusmc.nl

Engin Erturk
Karadeniz Technical University
Email: Engine_md@yahoo.com

Submit your article now

Manuscripts should be submitted as an attached file to an e-mail directed to the Chief Guest Editor, Ahmet Eroglu at the address: <erogluah@hotmail.com>

Special Issue on Towards a defined role of neoadjuvant chemotherapy in locally advanced cancer cervix

Background: Cervical cancer is the second most common cancer in women. It is responsible for 530,000 new cancer patients annually (9% of all new cancers diagnosed in women). (1)
Concurrent chemoradiotherapy (CCRT) is considered the standard treatment for locally advanced cancer cervix. A systematic review and meta-analysis of data showed survival benefits, better local and distant control of CCRT when compared with radiotherapy alone. (3, 4, 5)
However, CCRT is associated with considerable early toxicities, particularly gastrointestinal and hematological ones. Further, many studies showed significant rates of late side effects. The study of Tan, Zahra, 2008, and Green et al, 2001, showed grade 3/4 late sequelae in the range of18.3% to 22%, and included urinary, and, or bowel complications. (5, 6)
Rationale of neoadjuvant chemotherapy:
Several studies showed that neoadjuvant chemotherapy is effective in reducing tumor size, expediting micrometastasis, improving operability and surgical downstaging. Further, giving chemotherapy alone then surgery is associated with less side effects than giving chemotherapy and radiotherapy at the same time. (7, 8)
Many systemic reviews and meta-analysis showed benefits of neoadjuvant chemotherapy in terms of survival and toxicities. A recent systemic review showed neoadjuvant chemotherapy was associated with 5 year mean PFS of 61.9%, and 5 year OS of 72.8%. These results were comparable with CCRT in terms of survival, and early toxicities. Further, neoadjuvant chemotherapy had better late tocixity profile.
Till now, no published studies compared between neoadjuvant chemotherapy and CCRT.

Aim of the proposed study:
To assess the survival benefit, toxicities including long term toxicities for neoadjuvant chemotherapy versus CCRT in locally advanced cancer cervix.
Primary end point was survival benefits, and toxicities including long term related ones.

About the issue

The scope of topics covered in the this issue include:

  • Cancer Cervix, neoadjuvant chemotherapy
  • Brain Tumours: temozolmide, reirradiation in recurrent brain gliomas
  • Breast cancer: Beyond Taxenes
  • Urinary bladder cancer: neoadjuvant chemotherapy
  • Treatment related side effects, especially for long term survivors
  • Cancer correlation with obesity, and vitamin D deficiency
  • Molecular biology of cancer cells on recurrent, whether they are different from that at primary diagnosis

Important dates

Submission Deadline: November 01, 2014
Notification of Acceptance: December 01, 2014
Final Version Due: January 01, 2015
Special Issue Publishing Date: February 01, 2015

Chief Guest Editor

Mohammed A Osman
General organization for teaching hospitals, institutes, Egypt
Email: mmoneam@hotmail.com

Submit your article now

Manuscripts should be submitted as an attached file to an e-mail directed to the Chief Guest Editor, Mohammed A Osman at the address: <mmoneam@hotmail.com>