American Journal of Medical Sciences and Medicine
The Behçet’s syndrome is a systemic disorder in the crossroad between systemic vasculitis of small and large vessels affecting both veins and arteries and auto-inflammatory diseases.
This disease is present worldwide but its prevalence is the highest in the Middle East, Mediterranean region and Asia. Its onset is usually in the third decade. It is marked by relapsing and remitting course. Almost all patients with Behçet’s syndrome have recurrent oral aphthae, genital ulcers, variable skin lesions, such as erythema nodosum and papulopustuler lesions, arthritis, uveitis, thrombophlebitis, and gastrointestinal and central nervous system involvement. Although recent studies suggest the role of genetic and environmental factors, its pathogenesis remains unclear.
The treatment of Behçet disease continues to be based largely on anecdotal case reports, case series, and a few randomized clinical trials. Several scientific societies such European League Against Rheumatism (EULAR) have published guidelines for the treatment of Behçet’s syndrome. Despite their important contribution to better quality of the disease management, the Behçet syndrome can sometimes have poor prognosis especially in ocular, cardiovascular and neurological involvement.
This special issue aims:
1. To study the most important aspects of Behçet’s Syndrome focusing on epidemiology, different disease manifestations and diagnostic criteria.
2. To evaluate different therapeutic approaches including the biologic agents,
3. To explore the disease outcomes and study the different factors influencing the Behçet’s syndrome evolution.
About the issue
The scope of topics covered in the this issue include:
Submission Deadline: July 01, 2015Notification of Acceptance: July 20, 2015Final Version Due: August 01, 2015Special Issue Publishing Date: Septmber, 2015
Chief Guest Editor
Dr. Raouf HAJJI, MDInternal Medicine Department – Sidi Bouzid Regional Hospital – Ibn Aljazzar Medicine Faculty of Sousse - TunisiaEmail: email@example.com, firstname.lastname@example.org
Guest EditorDr. Fatma DERBALI, MDInternal Medicine Department – Sidi Bouzid Regional Hospital – Ibn Aljazzar Medicine Faculty of Sousse - TunisiaEmail: email@example.com
Dr. Kais MNAFGUI, PhDPathophysiology Laboratory – University of Sfax - TunisiaEmail: firstname.lastname@example.org
Submit your article now
Manuscripts should be submitted as an attached file to an e-mail directed to the Chief Guest Editor, Dr. Raouf HAJJI at the address: <email@example.com, firstname.lastname@example.org>
or through the journal’s Paper Submission System.
This special issue "Ethical Issues and Controversies in Medicine" focuses on the ethical issues, the dilemma of right and wrong, and the controversies that arise in the modern medical practice and research. Medical ethics is a system of moral principles that apply values and judgments to the practice of medicine. There is hardly an area in medicine that doesn't have an ethical aspect. In today’s society, medical treatment and decisions surrounding health care have become complex. It is therefore important to be knowledgeable and remain updated and aware of the issues that govern patient care. Although this special issue "Ethical Issues in Medicine" is primarily an organ of philosophical research, the journal seeks to publish the highest quality work on ethical issues and controversies that are topics of concern to academics and professionals who are directly or indirectly related to patient care.
Submission Deadline: March 15, 2015Notification of Acceptance: May 15, 2015Final Version Due: June 15, 2015Special Issue Publishing Date: July 15, 2015
Dr. Abhishek KarnDepartment of Forensic Medicine & Toxicology, U.C.M.S.T.H, NepalEmail: email@example.com
Guest EditorDr. Shivendra JhaDepartment of Forensic Medicine & Toxicology, B.P.K.I.H.S, NepalEmail: firstname.lastname@example.org
Dr. Birendra K. MandalDepartment of Forensic Medicine & Toxicology, C.M.C, NepalEmail: email@example.com
Manuscripts should be submitted as an attached file to an e-mail directed to the Chief Guest Editor, Dr. Abhishek Karn at the address: <firstname.lastname@example.org>
This special issue is essential reading for orthotists, prosthetists and all specialists studying how to substitute normal movement and how to coordinate it with injured / residual limb. Everybody has unique physical and physiological characteristics. They can be modified under load, in turn, results in propulsion. (e.g. plantar fascia thickness, angle of joints) To evaluate the amount of this modification in static and locomotion in living individual (not via calculation or modeling) can be scale / criteria to do dynamic alignment of orthosis / prosthesis. Subjects in the area of orthotics, prosthetics, biomechanics, plantar fascia structure and function, ankle and foot, physical and physiological behavior in symptomatic and asymptomatic population, new methods to evaluate tissues modification under load, to evaluate the amount of the applied load in static and locomotion, effect of lower limb deformities on ambulation, clinical management, can make accessible the objective of this special issue. As for lower extremities are weight bearing organs to ambulate, in asymptomatic population, the aim of this special issue is to promote the science to substitute lost movements with orthosis / prosthesis designed and aligned relying on physiological behavior and body weight , as close as possible, to the conditions and characteristics of unilateral user.
Submission Deadline: March 01, 2015Notification of Acceptance: May 01, 2015Final Version Due: July 01, 2015Special Issue Publishing Date: August 01, 2015
Sedegheh MalekMohammadiFaculty of Orthotics & Prosthetics / Iran University of Medical SciencesEmail: Sedigheh_mohammadi@yahoo.com
Manuscripts should be submitted as an attached file to an e-mail directed to the Chief Guest Editor, Sedegheh MalekMohammadi at the address: <Sedigheh_mohammadi@yahoo.com>
General anesthesia and regional anesthesia techniques are used in surgical procedures. Both intra-operative anesthesia and postoperative analgesia are important topics for patient and surgery. Some regional anesthesia techniques provide important advantages compared with general anesthesia for postoperative pain control in some surgical procedures. For example, epidural anesthesia, a regional anesthesia technique, is not only performed for adequate anesthesia in the surgical procedures but also for pain control. There are other advantages for the use of regional anesthesia techniques including excellent pain control, reduced side effects, improved cardiac and pulmonary function, and shortened stay in the post-anesthesia care unit. The use of regional anesthesia is also associated with decreased neuro-endocrine stress responses in the peri-operative period. Regional anesthesia is one of the important methods for multimodal postoperative pain control. Regional anesthesia would provide excellent pain control and improve outcome such as decrease in side effects, improvement of pulmonary function, prevention of chronic pain, or reduction in hospital stay. Thus the regional anesthetic techniques and outcome using regional anesthesia for postoperative pain have becoming one of the important fields. We invite authors to submit original research and review articles that seek to define the interaction between anesthesia and postoperative pain control. We are interested in articles that explore aspects of the effect of anesthesia techniques for pain control in humans and also in animal models.
The topics of this special issue include, but are not limited to:
Submission Deadline: October 27, 2014Notification of Acceptance: November 28, 2014Final Version Due: December 15, 2014Special Issue Publishing Date: December 29, 2014
Ahmet ErogluKaradeniz Technical UniversityEmail: email@example.com
Guest EditorCan InceErasmus University RotterdamEmail: firstname.lastname@example.org
Engin ErturkKaradeniz Technical UniversityEmail: Engine_md@yahoo.com
Manuscripts should be submitted as an attached file to an e-mail directed to the Chief Guest Editor, Ahmet Eroglu at the address: <email@example.com>
Background: Cervical cancer is the second most common cancer in women. It is responsible for 530,000 new cancer patients annually (9% of all new cancers diagnosed in women). (1)Concurrent chemoradiotherapy (CCRT) is considered the standard treatment for locally advanced cancer cervix. A systematic review and meta-analysis of data showed survival benefits, better local and distant control of CCRT when compared with radiotherapy alone. (3, 4, 5)However, CCRT is associated with considerable early toxicities, particularly gastrointestinal and hematological ones. Further, many studies showed significant rates of late side effects. The study of Tan, Zahra, 2008, and Green et al, 2001, showed grade 3/4 late sequelae in the range of18.3% to 22%, and included urinary, and, or bowel complications. (5, 6)Rationale of neoadjuvant chemotherapy:Several studies showed that neoadjuvant chemotherapy is effective in reducing tumor size, expediting micrometastasis, improving operability and surgical downstaging. Further, giving chemotherapy alone then surgery is associated with less side effects than giving chemotherapy and radiotherapy at the same time. (7, 8)Many systemic reviews and meta-analysis showed benefits of neoadjuvant chemotherapy in terms of survival and toxicities. A recent systemic review showed neoadjuvant chemotherapy was associated with 5 year mean PFS of 61.9%, and 5 year OS of 72.8%. These results were comparable with CCRT in terms of survival, and early toxicities. Further, neoadjuvant chemotherapy had better late tocixity profile.Till now, no published studies compared between neoadjuvant chemotherapy and CCRT.
Aim of the proposed study:To assess the survival benefit, toxicities including long term toxicities for neoadjuvant chemotherapy versus CCRT in locally advanced cancer cervix.Primary end point was survival benefits, and toxicities including long term related ones.
Submission Deadline: November 01, 2014Notification of Acceptance: December 01, 2014Final Version Due: January 01, 2015Special Issue Publishing Date: February 01, 2015
Mohammed A OsmanGeneral organization for teaching hospitals, institutes, EgyptEmail: firstname.lastname@example.org
Manuscripts should be submitted as an attached file to an e-mail directed to the Chief Guest Editor, Mohammed A Osman at the address: <email@example.com>