Journal of Food and Nutrition Research

ISSN (Print): 2333-1119

ISSN (Online): 2333-1240

Editor-in-Chief: Prabhat Kumar Mandal




Physicochemical Properties, Bioactive Compounds and Sensory Evaluation of Opuntia dillenii Fruits Mixtures

1Food Technology Department, Faculty of Agriculture, Suez Canal University, Ismailia, Post Code: 41522, Egypt

Journal of Food and Nutrition Research. 2016, 4(8), 528-534
doi: 10.12691/jfnr-4-8-7
Copyright © 2016 Science and Education Publishing

Cite this paper:
H.E. Embaby, A.A Gaballah, Y.S. Hamed, S.K. El-Samahy. Physicochemical Properties, Bioactive Compounds and Sensory Evaluation of Opuntia dillenii Fruits Mixtures. Journal of Food and Nutrition Research. 2016; 4(8):528-534. doi: 10.12691/jfnr-4-8-7.

Correspondence to: Y.S.  Hamed, Food Technology Department, Faculty of Agriculture, Suez Canal University, Ismailia, Post Code: 41522, Egypt. Email:


Color, bioactive compounds and sensory evaluation of five Opuntia dillenii drinks mixed with strawberry and barley were studied during storage under cooling (4±°C). It was found that Opuntia dillenii fruits had high levels of ascorbic acid (AA) (55.29 mg/100g), betacyanins (56.91), betaxanthin (45.64), total phenolic compounds (TCP) (179.30 mg/100g) and antioxidant capacity (AC) (53.32%). Mixtures with Opuntia dillenii had excellent red color and the ratio 3:1 (Opuntia dillenii: strawberry, T2) had the highest values of a*, color index and Chroma (20.18, 1.050 and 27.21 respectively). Also, the addition of Opuntia dillenii significantly increased the levels of AA, TCP and AC in all mixtures. Moreover, the mixture T2 had the highest levels of AA (18.67 mg/100m), TPC (71.12 mg/100ml) and AC (35.70 %). For sensory evaluation, all mixtures had acceptable properties and the mixtures of Opuntia dillenii with strawberry had better quality than those with barely. In addition, the mixture T2 had the best quality and stability during the storage. Therefore, Opuntia dillenii fruits can be successfully used to produce new drinks by mixing with strawberry and barley and the mixture T2 had the best properties and stability during the storage.



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Effect of Chromium Picolinate Supplementation on Diabetic Profile and Nutritional Status of the Type-2 Diabetic Adult Population – A Randomized Controlled Trial

1Department of Home & Health Sciences, Allama Iqbal Open University Islamabad, Pakistan

2Consultant Nutritionist, Shifa International Hospital, Sector H-8/4, Islamabad, Pakistan

Journal of Food and Nutrition Research. 2016, 4(8), 535-542
doi: 10.12691/jfnr-4-8-8
Copyright © 2016 Science and Education Publishing

Cite this paper:
Hajra Ahmad, Zaheer Ahmed, Rezzan Khan. Effect of Chromium Picolinate Supplementation on Diabetic Profile and Nutritional Status of the Type-2 Diabetic Adult Population – A Randomized Controlled Trial. Journal of Food and Nutrition Research. 2016; 4(8):535-542. doi: 10.12691/jfnr-4-8-8.

Correspondence to: Zaheer  Ahmed, Department of Home & Health Sciences, Allama Iqbal Open University Islamabad, Pakistan. Email:


The health impacts of Chromium Picolinate (CrP) have been searched by various researchers particularly focused on management of Type-2 Diabetes Mellitus (T2DM) with the conflicting results. The objective of the present study was to investigate the role of CrP on management of T2DM. It was a randomized controlled trial (RCT). Two groups of newly diagnosed Type -2 diabetics between the age brackets of 40-65 years were randomly selected from diabetes clinic. One group was exposed to 200 μg of CrP per day and the other was given a capsule of inert material as placebo having no impact on diabetic profile. The intervention duration was 03 months followed by one month as washout period. The outcome variables were biochemistry related to diabetic profile, clinical signs symptoms and toxicity if any. Dietary profile and anthropometrics were used for nutritional assessment. The study revealed that 82.7% of the subjects had family history of diabetes among which 59.6% were close relative. 98.1% were suffering from some kind of stress. Diabetic profile such as FPG, HbA1c and insulin levels improved in terms of normality after three months in treatment group, but did not come to the normal acceptable range e.g. The FPG dropped from142.85±17.71 to 130.42±32.68 mg/dl with a significant P value of 0.003 within the phases. Other health indicators such as lipid profile, blood pressure and clinical signs symptoms also improved and more in treatment group. Dietary counseling showed positive effects on food intake. Renal and hepatic profile showed no signs of toxicity in treatment group. The study concluded that CrP combined with dietary counseling had positive effect on diabetic profile of the newly diagnosed T2DM patients. The clinical signs and symptoms were improved. No hepatic and renal toxicity was observed.



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Hepatoprotective Activities of Huoshan Dendrobium Officinale Kimura et Migo Water Extracts on Carbontetrachloride-induced Hepatotoxicity in Mice

1Binzhou Medical University, Yantai, China

2Anhui Hushengji Biotechnology Co., Ltd., luan, China

3Pharmacy School of Shihezi University, Key Laboratory of Xinjiang Endemic Phytomedicine Resources, Ministry of Education, School of Pharmacy, Shihezi, China

Journal of Food and Nutrition Research. 2016, 4(8), 543-548
doi: 10.12691/jfnr-4-8-9
Copyright © 2016 Science and Education Publishing

Cite this paper:
Jichun Han, Defang Li, Xiaoyu Chen, Fanqing Meng, Bo Wang, Xinjie Zhang, Qiusheng Zheng. Hepatoprotective Activities of Huoshan Dendrobium Officinale Kimura et Migo Water Extracts on Carbontetrachloride-induced Hepatotoxicity in Mice. Journal of Food and Nutrition Research. 2016; 4(8):543-548. doi: 10.12691/jfnr-4-8-9.

Correspondence to: Qiusheng  Zheng, Binzhou Medical University, Yantai, China. Email:


Objective: The objective of this study is to investigate the hepatoprotective effects of water extracts from Huoshan Dendrobium officinale Kimura et Migo (HDW) in a mouse model of carbon tetrachloride (CCl4)-induced hepatotoxicity. In addition, potential mechanisms of any effects observed will be investigated. Methods: Mice received HDW pretreatment prior to induction of hepatotoxicity. HDW was administered to mice once daily for a total of 5 days (p.o.) at three dose levels (20, 100 and 500 mg/kg/day). Hepatotoxicity was then induced in Kunming mice using a single injection (s.c.) of CCl4. CCl4 was diluted in corn oil and used at a concentration of 10 ml/kg body weight. Levels of superoxide dismutase (SOD), malondialdehyde (MDA), glutathione disulfide (GSH) and glutathione disulfide (GSSG) were analyzed as a readout to measure oxidative stress status. Levels of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6) were measured as a readout of inflammation status. Levels of alanine aminotransferase (ALT) and aspartate aminotransferase (AST) were analyzed as a measure for the degree of hepatic injury. Finally, the liver ultrastructure was examined using optical microscopy. Results: CCl4-induced hepatotoxicity was shown to result in increased levels of ALT, AST, MDA, IL-6, CRP and TNF-ɑ, and decreased levels of SOD and a decreased GSH/GSSG ratio in serum. Histopathological examination of liver sections using microscopy revealed necrosis and inflammatory effects due to CCl4-induced hepatotoxicity. We observed that HDW pretreatment resulted in decreased levels of ALT, AST, MDA, IL-6, CRP and TNF-ɑ, and increased SOD levels and an increased GSH/GSSG ratio. In addition, the hepatic histo-architecture was shown to be normalized. Conclusion: This study provides support for the use of HDW to protect against toxic liver injury. Furthermore, we show that the hepatoprotective effects of HDW are likely attributed to its antioxidant and anti-inflammatory activities.



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