The field of security, intelligence and mobility in computer science has been one of the most emerging areas nowadays. With the progress of cyber technologies, many started believing that a computer could be a convenient, but, at the same time, a very safe place to work. Unfortunately, this is not the case because, as everything else, cyber era has its advantages and disadvantages. For that reason, cyber security becomes the ultimate goal for today’s computer experts as well as mobile and intelligence-driven systems. Cyber plane is strongly connected with risks and threats and it requires very skillful individuals to take part in it. From that perspective, the entire field of cyber science may appear as a big challenge for the future scientists and engineers. This Special Issue should focus on the main challenges that modern computer science faces up at the moment. The aim of the Special Issue would be to encourage new scientists and researchers to participate into exploring, discussing and understanding the novel ways and directions in the field of cyber science. The special attention would be paid to cyber defense, intelligent solutions, mobile technologies, strategic planning and many other areas of modern computing. The purpose of this Special Issue would be to bring together the newest and best research efforts and contributions which would be capable to present good reviews, current studies, modern analysis, novel models and maybe invoke some cutting-edge ideas regarding this field.