This proposal aims to discuss various types of hematologic malignancies, eg. Leukemia, lymphoma, myloma, etc. This special issue will concentrate on newer insights pertaining to the pathogenesis of various hematologic cancers, improved diagnostic tools, evaluation of current and future options of treatments as well as discussion on the place of stem cell transplantation in the overall management of patients. In addition, there will be emphasis on the mechanism of action of the novel agents in use and ways to improve them.
The aim of the Special Issue is to provide a platform for the researchers to understand the recent advancements and challenges in hematology oncology. These articles will provide an opportunity to the readers to understand and access the scientific information.
Scientific subjects will include articles concerning the epigenetic mechanisms of disease/therapy as well as the role of the immune system in hemato-oncology. Very interesting and uncommon subjects will include discussions of extramedullary disease and evaluations of the central nervous system by various imaging techniques. Experts will describe the role of hypomethylating agents in the management of hematologic malignancies and currently emerging and promising investigational therapies. Clinical success relies greatly on supportive therapy, and we will discuss supportive therapy, including infection prophylaxis. Allogeneic hematopoietic stem cell transplantation remains the most effective measure for curing aggressive hematologic malignancies, and a variety of topics will be considered: donor selection, age of recipient, which has been increasing seemingly without limit; therefore, recipient/donor assessments are more important than ever in the aging population. Alternative donor use (e.g., cord blood and haploidentical individuals) has been increasing dramatically; when and who should be considered, what is being investigated? With signi?cant changes occurring with respect to both donors and recipients, the pros and cons of using of anti-thymocyte globulin use in conditioning regimens will be also described.
About the issue
The topics of this special issue include, but are not limited to:
Submission Deadline: December 25, 2014
Notification of Acceptance: January 30, 2015
Final Version Due: February 25, 2015
Special Issue Publishing Date: March 20, 2015
Chief Guest Editor
Iman M. Fawzy, MD, PhD
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Manuscripts should be submitted as an attached file to an e-mail directed to the Chief Guest Editor, Iman M. Fawzy at the address: <Clinical.firstname.lastname@example.org>