American Journal of Medical Case Reports
ISSN (Print): 2374-2151 ISSN (Online): 2374-216X Website: Editor-in-chief: Samy, I. McFarlane
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American Journal of Medical Case Reports. 2021, 9(1), 57-61
DOI: 10.12691/ajmcr-9-1-14
Open AccessCase Report

Acute Parvovirus Infection Unmasking a Craniopharyngioma Causing Hypopituitarism

Yotam Kolben1, , Yuval Ishay1, Henny Azmanov1, Matan Fischer2, Nir Pillar3 and Simona Grozinsky-Glasberg4

1Department of Medicine, Hadassah - Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel

2Department of Endocrinology, Hadassah - Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel

3Department of Pathology, Hadassah - Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel

4Neuroendocrine Tumor Unit, ENETS Center of Excellence, Department of Endocrinology, Hadassah - Hebrew University Medical Center, Ein-Kerem, Jerusalem, Israel

Pub. Date: November 05, 2020

Cite this paper:
Yotam Kolben, Yuval Ishay, Henny Azmanov, Matan Fischer, Nir Pillar and Simona Grozinsky-Glasberg. Acute Parvovirus Infection Unmasking a Craniopharyngioma Causing Hypopituitarism. American Journal of Medical Case Reports. 2021; 9(1):57-61. doi: 10.12691/ajmcr-9-1-14


We present the case of a young male patient who arrived at the emergency room due to headache, constitutional and gastrointestinal symptoms. Upon presentation and during hospitalization, a complex clinical and chemical picture unfolded, and several diagnoses were considered. Eventually, it was concluded that panhypopituitarism secondary to craniopharyngioma was the cause of his symptoms. This long-standing condition was unmasked by an acute infection with Parvovirus. Treatment with hormone replacement therapy brought prompt improvement in both laboratory values and clinical condition.

parvovirus craniopharyngioma hypopituitarism

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