World Journal of Chemical Education
ISSN (Print): 2375-1665 ISSN (Online): 2375-1657 Website: Editor-in-chief: Prof. V. Jagannadham
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World Journal of Chemical Education. 2016, 4(5), 101-106
DOI: 10.12691/wjce-4-5-2
Open AccessArticle

A Highly Versatile One-Pot Aqueous Wittig Reaction

Forest J. Robertson1,

1Department of Chemistry, Western Connecticut State University, Danbury

Pub. Date: September 06, 2016

Cite this paper:
Forest J. Robertson. A Highly Versatile One-Pot Aqueous Wittig Reaction. World Journal of Chemical Education. 2016; 4(5):101-106. doi: 10.12691/wjce-4-5-2


The implementation of green chemistry experiments in the sophomore organic teaching lab is essential in order to increase student awareness of issues that pertain to sustainability and reducing waste that impacts the environment. Aspects of green chemistry that draw attention to these important issues include, but are not limited to, the use of safer solvents, the development of energy efficient reactions, the use of less hazardous chemicals, and the prevention of waste. To demonstrate the ease of introducing green chemistry principles into the organic chemistry teaching lab a Wittig reaction was chosen to be “greened.” The green Wittig reaction described within this report was performed at ambient temperature and in an aqueous medium; in addition, the reaction was complete within one hour, and the transformation was accomplished in “one-pot.” Finally, students analyzed the Wittig products using 1H NMR spectroscopy to confirm structure and to determine the E:Z ratio.

second-year undergraduate organic chemistry inquiry-based problem solving Wittig reaction green chemistry

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