World Journal of Chemical Education
ISSN (Print): 2375-1665 ISSN (Online): 2375-1657 Website: http://www.sciepub.com/journal/wjce Editor-in-chief: Prof. V. Jagannadham
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World Journal of Chemical Education. 2015, 3(1), 27-29
DOI: 10.12691/wjce-3-1-4
Open AccessArticle

Greener Synthesis of an Amide by Direct Reaction of an Acid and Amine under Catalytic Conditions

Gabriel Arce1, Gonzalo Carrau1, Ana Bellomo1 and David Gonzalez1,

1Depto. de Química Orgánica, Facultad de Química, Universidad de la República (UdelaR), Montevideo, Uruguay

Pub. Date: March 10, 2015

Cite this paper:
Gabriel Arce, Gonzalo Carrau, Ana Bellomo and David Gonzalez. Greener Synthesis of an Amide by Direct Reaction of an Acid and Amine under Catalytic Conditions. World Journal of Chemical Education. 2015; 3(1):27-29. doi: 10.12691/wjce-3-1-4

Abstract

A simple and high-yielding laboratory experiment that involves the boric acid catalyzed amidation of benzoic acid is described. The experiment makes use of recent chemistry, it is appropriate for advanced undergraduate chemistry students, and demonstrates several important concepts including homogeneous catalysis and green chemistry.

Keywords:
Upper-Division Undergraduate organic chemistry green chemistry catalysis amides

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