World Journal of Analytical Chemistry
ISSN (Print): 2333-1178 ISSN (Online): 2333-1283 Website: Editor-in-chief: Raluca-Ioana Stefan-van Staden
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World Journal of Analytical Chemistry. 2013, 1(4), 80-86
DOI: 10.12691/wjac-1-4-7
Open AccessReview Article

Various Analytical Methods for the Determination of Terazosin in Different Matrices

Alankar Shrivastava1,

1Department of Pharmaceutics, Institute of Biomedical Education and Research, Mangalayatan University, Aligarh, Uttar Pradesh, India

Pub. Date: December 08, 2013

Cite this paper:
Alankar Shrivastava. Various Analytical Methods for the Determination of Terazosin in Different Matrices. World Journal of Analytical Chemistry. 2013; 1(4):80-86. doi: 10.12691/wjac-1-4-7


Terazosin is used in men for symptom relief in the case of benign prostatic hyperplasia. This is categorized under the group of alpha one adrenoreceptor blockers. Terazosin is also used in high blood pressure by relaxing blood vessels so that blood can easily pass through. In this systematic review different analytical methods for the determination of terazosin in different matrices are discussed. Overall thirty six different analytical methods for the determination of terazosin were found in literature survey, 12 spectrophotometry, 2 TLC, 2 HPTLC, 16 HPLC and 4 electroanalytical methods were found. Advantages and disadvantages of available methods are also discussed. This review also adds knowledge about the place of terazosin therapy in hypertension or enlarged prostate. This review is useful for the researchers involved in the development of new analytical method or formulation.

Keywords: Terazosin spectrophotometry chromatography HPLC HPTLC method validation

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