Oral Surgery, Oral Medicine, Oral Radiology
ISSN (Print): 2379-5298 ISSN (Online): 2379-5301 Website: http://www.sciepub.com/journal/oral Editor-in-chief: Bouguezzi Adel
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Oral Surgery, Oral Medicine, Oral Radiology. 2015, 3(1), 20-24
DOI: 10.12691/oral-3-1-5
Open AccessA Clinical Study

The Effect of Mouth Rinsing with Stabilized Chlorine Dioxide on Periodontitis

Shuichi Tsubura1, 2, , Kimio Uchiyama2, 3, Manabu Yamada2, Osamu Mimori2, Shigeru Hiyama2, Katsuma Katoh2 and Masaki Shibata2

1Department of Biochemistry, The Nippon Dental University School of Life Dentistry at Niigata, Hamaura-cho, Chuo-ku, Niigata, Japan

2Department of Dentistry and Oral surgery, NHO Tochigi Medical Center, Nakatomatsuri, Utsunomiya, Tochigi, Japan

3Clinical Research Department, NHO Tochigi Medical Center, Nakatomatsuri, Utsunomiya, Tochigi, Japan

Pub. Date: August 02, 2015

Cite this paper:
Shuichi Tsubura, Kimio Uchiyama, Manabu Yamada, Osamu Mimori, Shigeru Hiyama, Katsuma Katoh and Masaki Shibata. The Effect of Mouth Rinsing with Stabilized Chlorine Dioxide on Periodontitis. Oral Surgery, Oral Medicine, Oral Radiology. 2015; 3(1):20-24. doi: 10.12691/oral-3-1-5


MATATACOROTM (containing 10 mg/l stabilized chlorine dioxide: MA-T, no alcohol, and is an odorless antibacterial agent) is useful for sterilization and disinfection. The aim of this study was to investigate whether MA-T is an appropriate mouth rinse for patients selected from whom undergoing initial periodontal treatment. The effect of rinsing with MA-T was compared with that with ConcoolTM (containing 0.05% chlorhexidine gluconate: CX), Neosterine GreenTM (containing 0.02% benzethonium chloride: NG), and purified water (PW). MA-T rinsing resulted in a marked change in the BANA-score and in the VAS scale. The mean BANA scores (score ± SD) on day 0 and day 30 were 1.55±0.50 and 0.4±0.50 (p<0.001) for MA-T, 1.65±0.48 and 0.75±0.44 for CX, 1.43±0.50 and 0.88±0.61 for NG, and 1.83±0.38 and 1.48±0.55 for PW, respectively. The intra-oral feeling caused by mouth rinsing was self-assessed using the VAS scores (mean ± SD) on day 0 and day 30; they were 48.23±14.70 and 74.43±7.33 (26.2 mm increase) for MA-T, 50.45±11.94 and 62.23±8.88 (11.8 mm increase) for CX, 54.13±8.11 and 63.73±8.18 (9.6 mm increase) for NG, and 54.70±6.06 and 59.18±6.11 (4.5 mm increase) for PW, respectively. These results suggest that MA-T induced marked reduction of periodontopathic oral bacteria and increased feeling of freshness after the treatment period. These results suggest that MA-T is an appropriate mouth rinse for patient with periodontitis.

stabilized chlorine dioxide mouth rinse periodontitis oral bacteria freshness

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