American Journal of Marine Science
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American Journal of Marine Science. 2016, 4(1), 1-3
DOI: 10.12691/marine-4-1-1
Open AccessArticle

Isolation and Screening of Marine Bacteria Producing Anti-Cancer Enzyme L-Asparaginase

M. Bhargavi1, and R. Jayamadhuri1

1Department of Applied Microbiology, Sri Padmavati Mahila Visvavidyalayam, Tirupati

Pub. Date: January 27, 2016

Cite this paper:
M. Bhargavi and R. Jayamadhuri. Isolation and Screening of Marine Bacteria Producing Anti-Cancer Enzyme L-Asparaginase. American Journal of Marine Science. 2016; 4(1):1-3. doi: 10.12691/marine-4-1-1


PURPOSE: The objective of this investigation was to isolation and screening of marine bacteria for L-asparaginase activity. METHODS: Marine bacteria were isolated from water samples obtained from Kerala sea coast in India. The isolates were identified as marine bacteria by microscopical and bio-chemical tests. Production of L-asparaginase was carried out in submerged fermentation media (glycerol asparagine media). RESULTS: Among three marine isolates subjected to screening only one isolate BKJM-VB showed potential L-asparaginase activity. CONCLUSION: The study revealed that marine bacteria may be a potential source of high yield, high substrate specificity L-asparaginase which is an anti-leukemic agent.

marine bacteria asparaginase sub merged fermentation

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