Journal of Polymer and Biopolymer Physics Chemistry
ISSN (Print): 2373-3403 ISSN (Online): 2373-3411 Website: http://www.sciepub.com/journal/jpbpc Editor-in-chief: Martin Alberto Masuelli
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Journal of Polymer and Biopolymer Physics Chemistry. 2015, 3(1), 1-5
DOI: 10.12691/jpbpc-3-1-1
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Acoustical Studies of Molecular Interactions in the Solution of Anti-Malarial Drug

Ritesh Ramdasji Naik1, , Sheshrao Vitthalrao Bawankar1 and Vilas Maruti Ghodki1

1Jankidevi Bajaj College of Science, Jamnalal Bajaj Marg, Civil Lines Wardha

Pub. Date: February 12, 2015

Cite this paper:
Ritesh Ramdasji Naik, Sheshrao Vitthalrao Bawankar and Vilas Maruti Ghodki. Acoustical Studies of Molecular Interactions in the Solution of Anti-Malarial Drug. Journal of Polymer and Biopolymer Physics Chemistry. 2015; 3(1):1-5. doi: 10.12691/jpbpc-3-1-1

Abstract

In the present study ultrasonic velocity (U), density (ρ) and viscosity (η) have been measured at frequency 1 MHz in the binary mixtures of chloroquine phosphate with water in the concentration range (0.1 to 0.0125 %) at 303 K,308 K,313 K using multi frequency ultrasonic interferometer. The measured value of density, ultrasonic velocity, and viscosity have been used to estimate the acoustical parameters namely adiabatic compressibility (βa), relaxation time (τ), acoustic impedance (z), free length (Lf), free volume (Vf) and internal pressure (Πi), Wada’s constant (W) to investigate the nature and strength of molecular interaction in the binary mixture of chloroquine phosphate hydrochloride with water. The obtained result supports the complex formation, molecular association by intermolecular hydrogen bonding in the binary liquid mixtures.

Keywords:
chloroquine phosphate free volume acoustical parameters ultrasonic velocity

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