Journal of Polymer and Biopolymer Physics Chemistry
ISSN (Print): 2373-3403 ISSN (Online): 2373-3411 Website: Editor-in-chief: Martin Alberto Masuelli
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Journal of Polymer and Biopolymer Physics Chemistry. 2014, 2(4), 62-66
DOI: 10.12691/jpbpc-2-4-1
Open AccessArticle

Fabrication of Poly(Caprolactone) Nanofibers by Electrospinning

Athira K. S.1, , Pallab Sanpui1 and Kaushik Chatterjee1

1Biomaterials and Tissue Engineering Laboratory, Department of Materials Engineering, Indian Institute of Science, Bangalore, India

Pub. Date: November 09, 2014

Cite this paper:
Athira K. S., Pallab Sanpui and Kaushik Chatterjee. Fabrication of Poly(Caprolactone) Nanofibers by Electrospinning. Journal of Polymer and Biopolymer Physics Chemistry. 2014; 2(4):62-66. doi: 10.12691/jpbpc-2-4-1


Nanofibers at 466 ± 242 nm average diameter were fabricated due to phase separation caused by polarizability difference under static electric field. Fibre morphology was observed under a scanning electron microscopy. An insight into the process of electrospinning of the polymer, poly(caprolactone) was systematically evaluated and discussed the effects of the solution parameter of concentration of the polymer solution and process parameters of voltage, flow rate and drop height to fabricate poly(caprolactone) electrospun fibers with desired morphologies in this manuscript. Of all combinations, the best nanofibres with the fewest beads and finest fibers could be electrospun with a more uniform distribution in with a 15 kV applied voltage of on poly(caprolactone) solution of 12 per cent concentration at a 0.5 ml/h flow rate, from a drop height of 15 cm and the structure of nanofibres was found completely dry and stabilized.

electrospinning polymer solution parameters process parameters Poly(caprolactone) nanofiber

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[1]  Sukigara, S., Gandhi, M., Ayutsede, J., Micklus, M. and Ko, F, “Regeneration of Bombyx morisilk by electrospinning-part 1: processing parameters and geometric properties,” Polymer, 44, 5721-5727, 2003.
[2]  Haghi, A.K. and Akbari, M, “Trends in electrospinning of natural nanofibers,” Phys Status Solidi., 204, 1830–1834, 2007.
[3]  Ki, C.S., Baek, D.H., Gang, K.D., Lee, K.H., Um, I.C. and Park, Y.H, “Characterization of gelatin nanofiber prepared from gelatin-formic acid solution,” Polymer., 46, 5094-5102, 2005.
[4]  Jun, Z., Hou, H., Schaper, A., Wendorff, J.H. and Greiner, A, “Poly-L-lactide nanofibers by electrospinning-influence of solution viscosity and electrical conductivity on fiber diameter and fiber morphology,” e-Polym., 9, 1-9, 2003.
[5]  Deitzel, J.M., Kleinmeyer, J., Harris, D. and Tan, N.C.B, “The effect of processing variables on the morphology of electrospun nanofibers and textiles,” Polymer., 42, 261-272, 2001.
[6]  Baumgarten, P.K, “Electrostatic spinning of acrylic microfibers,” J Colloid Interface Sci., 36, 71-79, 1971.
[7]  Reneker, D.H. and Chun, L, “Nanometre diameters of polymer, produced by electrospinning,” Nanotechnology, 7, 216-223, 1996.
[8]  Zhang, C., Yuan, X., Wu, L., Han, Y. and Sheng, J, “Study on morphology of electrospun poly(vinyl alcohol) mats,” Eur Polym J., 41, 423-432, 2005.
[9]  Demir, M.M., Yilgor, I., Yilgor, E. and Erman, B, “Electrospinning of polyurethanefibers,” Polymer., 43, 3303-3309, 2002.
[10]  Larrondo, L. and Manley, R.S.J, “Electrostatic fiber spinning from polymer melts. II. Examination of the flow field in an electrically driven jet,” J Polym Sci Polym Phys Ed., 19, 921-932, 1981.
[11]  Yordem, O.S., Papila, M. and Menceloğlu, Y.Z, “Effects of electrospinning parameters on polyacrylonitrile nanofiber diameter: an investigation by response surface methodology,” Mater Des., 29, 34-44, 2008.
[12]  Yuan, X.Y., Zhang, Y.Y., Dong, C.H. and Sheng, J, “Morphology of ultrafine polysulfone fibers prepared by electrospinning,” Polym Int., 53, 1704-1710, 2004.
[13]  Zuo, W.W., Zhu, M.F., Yang, W., Yu, H., Chen, Y.M. and Zhang, Y, “Experimental study on relationship between jet instability and formation of beaded fibers during electrospinning,” Polym Eng Sci., 45, 704-709, 2005.
[14]  Bharadwaj, N. and Kundu, S.C, “Electrospinning: A fascinating fiber fabrication technique,” Biotechnology Advances., 28, 325-347, 2010.
[15]  Jalili, R., Hosseini, S.A. and Morshed, M, “The effects of operating parameters on the morphology of electrospun polyacrilonitrile nanofibres,” Iran Polym J., 14, 1074-1081, 2005.
[16]  Lee, J.S., Choi, K.H., Ghim, H.D., Kim, S.S., Chun, D.H. and Kim, H.Y, “Role of molecular weight of a tactic poly (vinyl alcohol) (PVA) in the structure and properties of PVA nanofabric prepared by electrospinning,” J Appl Polym Sci., 93, 1638-1646, 2004.
[17]  Buchko, C.J., Chen, L.C., Shen, Y. and Martin, D.C, “Processing and microstructural characterization of porous biocompatible protein polymer thin films,” Polymer., 40, 7397-7407, 1999.
[18]  Pham, Q.P., Sharma, U. and Mikos, A.G, “Electrospun poly (ε-caprolactone) microfiber and multilayer nanofiber/microfiber scaffolds: characterization of scaffolds and measurement of cellular infiltration,” Biomacromolecules., 7, 2796-2805, 2006.
[19]  Zhao, Z.Z., Li, J.Q., Yuan, X.Y., Li, X., Zhang, Y.Y. and Sheng, J, “Preparation and properties of electrospun poly (vinylidenefluoride) membranes,” J Appl Polym Sci., 97, 466-474, 2005.