Journal of Food and Nutrition Research
ISSN (Print): 2333-1119 ISSN (Online): 2333-1240 Website: Editor-in-chief: Prabhat Kumar Mandal
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Journal of Food and Nutrition Research. 2018, 6(10), 655-659
DOI: 10.12691/jfnr-6-10-6
Open AccessArticle

Effect of Oral Intake of A Mixture Containing Natural Citrus Peel Extract, Vitamin C, and L-Cystine on Skin Brightness in Healthy Women

Jeong Kee Kim1, Nok Hyun Park1, Jae Sung Hwang1, Ji Hoon Baek2 and Hyun Woo Jeong3,

1Department of Genetic Engineering & Graduate School of Biotechnology, College of Life Sciences, Kyung Hee University, Yongin, Korea

2Dermapro Skin Research Center, Dermapro Ltd., Seoul, Korea

3Vitalbeautie Research Institute, Amorepacific Corporation R&D center, Yongin, Korea

Pub. Date: November 15, 2018

Cite this paper:
Jeong Kee Kim, Nok Hyun Park, Jae Sung Hwang, Ji Hoon Baek and Hyun Woo Jeong. Effect of Oral Intake of A Mixture Containing Natural Citrus Peel Extract, Vitamin C, and L-Cystine on Skin Brightness in Healthy Women. Journal of Food and Nutrition Research. 2018; 6(10):655-659. doi: 10.12691/jfnr-6-10-6


Citrus peel extract (CPE) has several bioactivities that encompass anti-oxidation, anti-inflammation and anti-melanogenic effect. However, its usage in functional food has been difficult due to uncommon evidence in human trial. The reason of this study is to evaluate the safety and skin brightening effects of natural CPE in human subjects. To enhance its effectiveness in clinical trial, we also used both vitamin C for anti-oxidation and L-cystine for decreasing melanin biosynthesis. All subjects administered 1 test capsule (AP-BF02 including 100mg of CPE, 125mg of vitamin C, 60mg of L-cystine) or placebo for two months. We objectively measured changes in melanin index (MI), skin lightness (L*), and skin color (ITAO). The two investigators also used subjective ratings to analyze skin pigmentation. The MI values were significantly lower in test group, compared with that in placebo group from 4 weeks after. In addition, AP-BF02-intake group had significant improvement in lightness and color at the end of examine period. Consequently, oral supplementation with AP-BF02 can brighten human skin in healthy women without adverse effect.

melanin skin brightening AP-BF02 citrus peel extract human natural skin food

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