Journal of Food and Nutrition Research
ISSN (Print): 2333-1119 ISSN (Online): 2333-1240 Website: Editor-in-chief: Prabhat Kumar Mandal
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Journal of Food and Nutrition Research. 2017, 5(7), 518-521
DOI: 10.12691/jfnr-5-7-10
Open AccessArticle

Effect of Aqueous Extract of Dendropanax morbifera Leaf on Sexual Behavior in Male Rats

Myung-A Jung1, 2, Kyo-nyeo Oh1, Eun Jin Choi1, Yu jin Kim1, Donghyuck Bae1, Dool-Ri Oh1, Ki man Kim3, Dong-Wook Kim2 and Chul-yung Choi1,

1Jeonnam Bioindustry Foundation, Jeonnam Insittute on Natural Resources Research, Jeollanamdo, South Korea

2Department of Oriental Medicine Resources, College of Natural Science, Mokpo National University, Jeollanamdo, South Korea

3Serom Co., Ltd., Jeollanamdo, South Korea

Pub. Date: July 14, 2017

Cite this paper:
Myung-A Jung, Kyo-nyeo Oh, Eun Jin Choi, Yu jin Kim, Donghyuck Bae, Dool-Ri Oh, Ki man Kim, Dong-Wook Kim and Chul-yung Choi. Effect of Aqueous Extract of Dendropanax morbifera Leaf on Sexual Behavior in Male Rats. Journal of Food and Nutrition Research. 2017; 5(7):518-521. doi: 10.12691/jfnr-5-7-10


Sexual function in an important of the quality of life and subjective well-being in humans. Successful treatment of sexual dysfunction may improve not only sexual relationships, but also overall quality of life. The objective of this study was to determine the effects of Dendropanax morbifera (DM) Lev. leaf extracts on sexual behavior and testosterone levels in male rats. Three different doses of DM (50, 100, and 200 mg/kg/day) were administered orally for 28 days. On day 28 (final day of the sample treatment period) and day 42 (after 2 weeks of sample withdrawal period following 28 days of sample treatment), serum testosterone levels and sexual behavior of rats were determined, including mount frequency (MF), intromission frequency, mount latency (ML, the time from introduction of the female to the male to the first mount), intromission latency (IL), and post-ejaculatory interval (PEI). ML significantly reduced, whereas MF increased in the DM group. The DM group also had a reduced PEI. The oral administration of DM significantly increased serum testosterone levels compared with those in the control group. The results of this study demonstrate that an aqueous extract of DM represents a useful natural resource for the management of sexual function.

sexual behavior testosterone erectile dysfunction Dendropanax morbifera

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