Journal of Food and Nutrition Research
ISSN (Print): 2333-1119 ISSN (Online): 2333-1240 Website: http://www.sciepub.com/journal/jfnr Editor-in-chief: Prabhat Kumar Mandal
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Journal of Food and Nutrition Research. 2017, 5(7), 490-495
DOI: 10.12691/jfnr-5-7-6
Open AccessArticle

Anticancer, Antimicrobial and Antioxidant Activities of the Essential Oils of Some Aromatic Medicinal Plants (Pulicaria inuloides-Asteraceae)

Nabil Qaid M. Al-Hajj1, 2, Algabr MN3, Khamis Ali Omar1 and Hongxin Wang1,

1School of Food Science and Technology, Jiangnan University, Wuxi 214122, P.R. China

2Marine Science and Biological Research Authority, Aden, P.O. Box-1231, Aden, Yemen

3Hajjah University, Department of chemistry, Faculty of Applied Science, P.O. Box 80004, Yemen

Pub. Date: June 28, 2017

Cite this paper:
Nabil Qaid M. Al-Hajj, Algabr MN, Khamis Ali Omar and Hongxin Wang. Anticancer, Antimicrobial and Antioxidant Activities of the Essential Oils of Some Aromatic Medicinal Plants (Pulicaria inuloides-Asteraceae). Journal of Food and Nutrition Research. 2017; 5(7):490-495. doi: 10.12691/jfnr-5-7-6

Abstract

Purpose: To determine the anticancer, antimicrobial and antioxidant activities of Pulicaria inuloides essential oil (PiEO). Methods: 3-(4, 5-dimethylthiazol- 2-yl)-2, 5-diphenyltetrazolium bromide (MTT) was used to assess cytotoxic activity. Steam distillation of the aerial parts of P. inuloides was performed using a Clevenger apparatus. Antioxidant activities were determined by using 2, 2-diphenyl-1,1-picrylhydrazyl (DPPH). Disc diffusion and microtiter broth microdilution assays were employed to determine antimicrobial activity. Results: PiEO inhibited six tested strains of Listeria with minimum inhibitory concentrations of 5.49 μg/mL against L. monocytogenes, L. innocua, and L. ivanovii; 6.24 μg/mL against L. welshimeri, and L. grayi; and 11.55 μg/mL against L. seeligeri. PiEO also possessed more efficient free radical scavenging activities than butylated hydroxytoluene (BHT). PiEO possessed significant anticancer properties, indicated by growth inhibition and changes in the morphological structure of MCF-7 cancer cells treated with PiEO.

Keywords:
Pulicaria inuloides essential oil MCF-7 antimicrobial antioxidant activity

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