Journal of Food and Nutrition Research
ISSN (Print): 2333-1119 ISSN (Online): 2333-1240 Website: Editor-in-chief: Prabhat Kumar Mandal
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Journal of Food and Nutrition Research. 2017, 5(3), 176-179
DOI: 10.12691/jfnr-5-3-6
Open AccessCommunication

Optimal Conditions for Extracting the Ginsenosides Rg3, Rg5, and Rk1 from Black Ginseng

Myo Jin Kwon1, Kui-Jin Kim2, Byung Wook Yang3, Boo-Yong Lee2, Hyoung Chun Kim4, and Sung Kwon Ko1, 3,

1Department of Oriental Medical Food & Nutrition, Semyung University, Jecheon, Republic of Korea

2Department of Food Science and Biotechnology, CHA University, Seongnam, Republic of Korea

3Ginseng Research Center, Koyeon, Jecheon, Republic of Korea

4College of Pharmacy, Kangwon National University, Chunchon, Republic of Korea

Pub. Date: March 11, 2017

Cite this paper:
Myo Jin Kwon, Kui-Jin Kim, Byung Wook Yang, Boo-Yong Lee, Hyoung Chun Kim and Sung Kwon Ko. Optimal Conditions for Extracting the Ginsenosides Rg3, Rg5, and Rk1 from Black Ginseng. Journal of Food and Nutrition Research. 2017; 5(3):176-179. doi: 10.12691/jfnr-5-3-6


Ginseng is known to contain numerous ginsenosides, which exhibit beneficial health effects. In particular, ginsenoside Rg3, Rg5, and Rk1, derived from high temperature-processed ginseng, have higher bioactivities compared to other types of ginsenosides. In this study, we determined the optimal conditions for extraction of the valuable ginsenosides Rg3, Rg5, and Rk1 from black ginseng. Our results revealed that black ginseng extracted with 100°C distilled water for 0.5 hours and 6 hours yields large amounts of Rg3, Rg5, and Rk1 compared with other extraction times. We also found that protopanaxadiol (PPD) and protopanaxatriol (PPT) were also efficiently extracted from black ginseng with 100 °C distilled water at 0.5 hours and 6 hours and then rapidly degraded in a time-dependent manner. Therefore, we posit that short extraction times such as 0.5 hours and 6 hours might be optimal for isolation of the ginsenosides Rg3, Rg5, and Rk1 from black ginseng as opposed to longer extraction periods.

black ginseng ginsenoside prosapogenin protopanaxadiol protopanaxatriol Rg3 Rg5 Rk1

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