Journal of Food and Nutrition Research
ISSN (Print): 2333-1119 ISSN (Online): 2333-1240 Website: Editor-in-chief: Prabhat Kumar Mandal
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Journal of Food and Nutrition Research. 2016, 4(4), 201-204
DOI: 10.12691/jfnr-4-4-1
Open AccessArticle

Relationship between Inflammation and Handgrip Strength among Non-critical Inpatients

Zhiwen Ge1, Zhongxin Hong1, , Jia Wang1, Bingjie Ding1, Lihong Zhang1, Wei Li1, Yanxia Bi1, Zhongyi Gu1, Weihua Qu1 and Li Wu1

1Department of Nutrition, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China

Pub. Date: May 04, 2016

Cite this paper:
Zhiwen Ge, Zhongxin Hong, Jia Wang, Bingjie Ding, Lihong Zhang, Wei Li, Yanxia Bi, Zhongyi Gu, Weihua Qu and Li Wu. Relationship between Inflammation and Handgrip Strength among Non-critical Inpatients. Journal of Food and Nutrition Research. 2016; 4(4):201-204. doi: 10.12691/jfnr-4-4-1


Purpose: To analyze the relationship between inflammation and handgrip strength (HGS), an indicator of nutritional status, in inpatients with non-critical illnesses. Materials and Methods: HGS was measured in 530 inpatients (mean age = 56.4 ± 15.2 years) with a handgrip dynamometer. Nutrition risk was evaluated by administration of the nutrition risk screening–2002 tool. High-sensitivity C reactive protein (hs-CRP) measurements were made with an immuno-turbidimetric assay. Linear regression was used to assess relationships between variables. T-tests, Mann-Whitney U tests, and Kruskal-Wallis H tests were used to detect significant differences. Results: After accounting for gender, age, and nutrition risk, hs-CRP level was a significant predictor of HGS (β-coefficient = -0.1, p < 0.05). Conclusion: HGS was associated inversely with inflammation in hospitalized patients with non-critical illnesses. This finding suggests that relieving inflammation may benefit HGS, which could potentially lead to improved outcomes in terms of relief of inflammation, shorter hospital stays, decreased re-hospitalization rates, and decreased mortality rates.

HGS inflammation high-sensitivity-c reactive protein inpatients non-critical illness

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