Journal of Food and Nutrition Research
ISSN (Print): 2333-1119 ISSN (Online): 2333-1240 Website: Editor-in-chief: Prabhat Kumar Mandal
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Journal of Food and Nutrition Research. 2015, 3(9), 587-592
DOI: 10.12691/jfnr-3-9-5
Open AccessArticle

Free Radical-scavenging, Nitrite-scavenging, and N-nitrosamine Formation Inhibitory Activities of Extracts from Kunlun Compositae Tea (Coreopsis tinctoria Nutt.)

Xincheng Yao1, 2, Ting Zhang1, Hui Tang1, 2, , Heng Wang1 and Wen Chen1, 2

1School of Pharmacy, Shihezi University, Shihezi, Xinjiang, P.R.China

2Key Laboratory of Xinjiang Endemic Phytomedicine Resources, Ministry of Education, Shihezi University, Shihezi, Xinjiang, P.R.China

Pub. Date: November 19, 2015

Cite this paper:
Xincheng Yao, Ting Zhang, Hui Tang, Heng Wang and Wen Chen. Free Radical-scavenging, Nitrite-scavenging, and N-nitrosamine Formation Inhibitory Activities of Extracts from Kunlun Compositae Tea (Coreopsis tinctoria Nutt.). Journal of Food and Nutrition Research. 2015; 3(9):587-592. doi: 10.12691/jfnr-3-9-5


Coreopsis tinctoria Nutt., Asteraceae, is widely used as an ornamental plant and as a popular tea production in China. In this paper, we report about the free radical-scavenging, nitrite-scavenging and N-nitrosamine formation inhibitory activities of ethyl acetate extract (EAE) and n-butanol extract (BE) of C. tinctoria flowering tops (CTF). The results showed the BE contained higher total phenolic content (TPC) , total flavonoid content (TFC) and total proanthocyanidin (TPA) contents with DPPH, ABTS and *OH radical-scavenging activities (IC50) of 25.79±2.753, 26.61±3.158 and 2349.8±0.672 μg/ml, respectively. However, EAE showed higher radical-scavenging activities, with IC50 ABTS and *OH values of 13.71±2.973 and 321.6±0.576 μg/ml, respectively. The nitrite-scavenging and N-nitrosamine inhibitory activities (IC50) of EAE were 122.10±1.03 and 2362.86±11.26 μg/ml, respectively, whereas those of BE were 118.23±1.30 and 2182.79±10.74 μg/ml, respectively. Given these activities, we propose that CTF can be potentially used as a rich source of natural free radical and nitrite scavengers.

radical-scavenging activity nitrite-scavenging activity N-nitrosamine formation inhibitory activity Coreopsis tinctoria Nutt

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