Journal of Food and Nutrition Research
ISSN (Print): 2333-1119 ISSN (Online): 2333-1240 Website: Editor-in-chief: Prabhat Kumar Mandal
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Journal of Food and Nutrition Research. 2020, 8(6), 279-287
DOI: 10.12691/jfnr-8-6-6
Open AccessArticle

A Clinical Investigation: A Weight Loss Kit with a Prebiotic Formula for Weight Management and Metabolic Improvement

Hui-Chun Chang1, Bo-Han Wu2, Yen-Ju Lin3, Yung-Hao Lin3, Yung-Hsiang Lin1 and Chen-Meng Kuan1,

1Research & Design Center, TCI CO., Ltd., Taipei, Taiwan

2Department of Recreation Sport and Health Promotion, Pingtung University of Science and Technology, Pingtung 912, Taiwan

3Research & Design Center, TCI Gene Inc., Taipei 114, Taiwan

Pub. Date: July 15, 2020

Cite this paper:
Hui-Chun Chang, Bo-Han Wu, Yen-Ju Lin, Yung-Hao Lin, Yung-Hsiang Lin and Chen-Meng Kuan. A Clinical Investigation: A Weight Loss Kit with a Prebiotic Formula for Weight Management and Metabolic Improvement. Journal of Food and Nutrition Research. 2020; 8(6):279-287. doi: 10.12691/jfnr-8-6-6


This preliminary clinical study reveals the possibilities of a weight loss kit with a prebiotic formula for weight management and metabolic improvement in volunteers. Considering the convenience, passive diets are a popular choice for some people for weight management. However, the synergic effect between passive diet kits and prebiotics has seldom been reported. 90 volunteers were enrolled in this two-month study and assigned them to normal diet (ND), weight loss program kit (WLPK), or WLPK with the prebiotic formula (WLPK-AKK) group based on purposive sampling. Anthropometric measurements, biochemical analysis, and fecal microbiome analysis were conducted at the baseline and 1 and 2 months. The prebiotic formula could reduce weight mass, fat mass, visceral fat, body fat percentage, triglyceride, total cholesterol, and LDL cholesterol of the subjects by 0.5 kg, 0.7 kg, 9 cm2, 0.6%, 2%, 1.6%, 1.2%, respectively. Also, it improved the abundance of A. muciniphila by 250% in comparison with the control group. In short, this study demonstrates that the weight loss kit with the prebiotic formula enables to facilitate the abundance of probiotics in the human intestines and comprehensively improve body weight and metabolic disorders.

prebiotic obesity overweight weight loss metabolic improvement

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