Journal of Food and Nutrition Research
ISSN (Print): 2333-1119 ISSN (Online): 2333-1240 Website: Editor-in-chief: Prabhat Kumar Mandal
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Journal of Food and Nutrition Research. 2020, 8(6), 268-272
DOI: 10.12691/jfnr-8-6-4
Open AccessArticle

Investigation of the Synergistic Effect of Berry Juice and Xylooligosaccharides on Skin Health: A Clinical Evaluation

Hui-Chun Chang1, Chia-Hua Liang2, Yen-Ju Lin3, Yung-Hao Lin3, Yung-Hsiang Lin1 and Chen-Meng Kuan1,

1Research & Design Center, TCI CO., Ltd., Taipei, Taiwan

2Department of Cosmetic Science and Institute of Cosmetic Science, Chia Nan University of Pharmacy and Science, Tainan 717, Taiwan

3Research & Design Center, TCI Gene Inc., Taipei 114, Taiwan

Pub. Date: July 12, 2020

Cite this paper:
Hui-Chun Chang, Chia-Hua Liang, Yen-Ju Lin, Yung-Hao Lin, Yung-Hsiang Lin and Chen-Meng Kuan. Investigation of the Synergistic Effect of Berry Juice and Xylooligosaccharides on Skin Health: A Clinical Evaluation. Journal of Food and Nutrition Research. 2020; 8(6):268-272. doi: 10.12691/jfnr-8-6-4


This preliminary clinical study demonstrates the possibility of a prebiotic juice for improvement of skin conditions. Recently, the health benefits of probiotics and prebiotics for prevention/treatment of diseases have been underscored in the medical field. However, it is challenging to uphold the viability of probiotics in drinks with low pH ranges (e.g., juices), while prebiotics are possible to overcome the impediment. In this study, we utilized a berry juice with xylooligosaccharides (XOS) to explore the clinical benefits for skin heath. There is little clinical evidence for the XOS applications in anti-aging. After 8-week juice-XOS intervention, in comparison with the baseline results, the mean levels of skin brightness, moisture, elasticity, spots, UV spots, and brown spots of subjects were improved by 2.7%, 11%, 5.1%, 3.1%, 6.2%, and 0.6%, respectively. Besides UV spots, the results of other skin parameters at 8 weeks in juice-XOS group were significantly different from the baseline results. Nevertheless, juice-XOS did not exert an obvious improving effect on body composition since the XOS content was too few to impart a remarkable improving effect on metabolism as evidenced by the previous reports. In brief, we demonstrated that prebiotic juice may provide an alternative route to daily skincare although the underlying mechanism of juice-XOS for improvement of skin health is not clear.

xylooligosaccharides berry juice skin aging anti-aging

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