Journal of Food and Nutrition Research
ISSN (Print): 2333-1119 ISSN (Online): 2333-1240 Website: Editor-in-chief: Prabhat Kumar Mandal
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Journal of Food and Nutrition Research. 2020, 8(3), 155-159
DOI: 10.12691/jfnr-8-3-6
Open AccessArticle

Pear Formula for Respiratory Care

Ping Lin1, Kai-Wen Kan2, Jia-Haur Chen2, Yung-Kai Lin3, Yung-Hao Lin4, Yung-Hsiang Lin1 and Chen-Meng Kuan1,

1Research & Design Center, TCI CO., Ltd., Taipei, Taiwan

2Research & Design Center, TCI Gene Inc., Taipei, Taiwan

3Department of Animal Science, Chinese Culture University, Taipei, Taiwan

4Global Business Center, TCI CO., Ltd., Taipei, Taiwan

Pub. Date: March 28, 2020

Cite this paper:
Ping Lin, Kai-Wen Kan, Jia-Haur Chen, Yung-Kai Lin, Yung-Hao Lin, Yung-Hsiang Lin and Chen-Meng Kuan. Pear Formula for Respiratory Care. Journal of Food and Nutrition Research. 2020; 8(3):155-159. doi: 10.12691/jfnr-8-3-6


This study unveils the possibility of a pear-based formula for reparatory care. Pears contain abundant polyphenols and triterpenoids in their fruit and skin, which confer antoxidative and anti-inflammatory effects on the prevention of chronic diseases. Pears have been used in several traditional remedies for reliving respiratory syndromes and constipation for over 2000 years in China. However, the use of pears for daily care is not easily accessible for most people. A pear-based sachet is a convenient approach to the beneficial ingredients of pears. The pear-based formula here enhanced wound healing rate by 27% and significantly improved the expression of allergy-, lung disease-, and DNA repair-related genes in lung cells. Moreover, the formula could increase the phagocytic activity of macrophages by 43%. In short, pear-based formula might provide the comprehensive respiratory care as evidenced by improvement in the wound healing efficiency of lung cells, the phagocytic activity of macrophages, down-regulation of the expression of respiratory disease-associated genes, and up-regulation the expression of DNA mismatch repair genes in cellular models.

pear antioxidation phagocytosis mismatch DNA repair wound healing

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