Journal of Environment Pollution and Human Health
ISSN (Print): 2334-3397 ISSN (Online): 2334-3494 Website: http://www.sciepub.com/journal/jephh Editor-in-chief: Dibyendu Banerjee
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Journal of Environment Pollution and Human Health. 2016, 4(3), 66-71
DOI: 10.12691/jephh-4-3-2
Open AccessReview Article

The Effect of Air Pollution on Cancer in the Eastern Mediterranean Region: A Systematic Literature Review

Yousef S Khader1, , Nour Abdo1, Mostafa Abdelrahman2, Munjed Al-Sharif3, Ahmad M. Bateiha4 and Mazen Malkawi5

1Department of Public Health/ Faculty of Medicine, Jordan University of Science and Technology

2Faculty of Applied Medical Sciences, Jordan University of Science and Technology, P.O.Box 3030, Irbid 22110, Jordan

3Water and Environmental Engineering Department, German-Jordanian University

4Department of Applied Biological Sciences, Jordan University of Science and Technology

5Centre for Environmental Health Activities, Regional Office for the Eastern Mediterranean, WHO, Genève, Schweizer

Pub. Date: September 24, 2016

Cite this paper:
Yousef S Khader, Nour Abdo, Mostafa Abdelrahman, Munjed Al-Sharif, Ahmad M. Bateiha and Mazen Malkawi. The Effect of Air Pollution on Cancer in the Eastern Mediterranean Region: A Systematic Literature Review. Journal of Environment Pollution and Human Health. 2016; 4(3):66-71. doi: 10.12691/jephh-4-3-2

Abstract

This study was conducted to assess the risk of cancer associated with air pollution in Eastern Mediterranean Region (EMR) by summarizing the existing knowledge from previous studies in the region and to identify knowledge and research gaps to support further research efforts. Combinations of search terms from three categories (“country” keywords AND ‘air pollution” keywords AND “cancer” keywords) were used to search for the relevant literature published between January 2000 and June 2016 using MEDLINE and other databases. Six case-control studies and three studies of other designs had assessed the association between air pollution and cancer in the EMR and met the inclusion criteria. These studies have assessed the effect of various indoor and outdoor air pollutants on the risk of different types of cancer. In this review, cancers were classified into: lung cancer; nasopharyngeal cancer; urinary bladder cancer; overall incidence of cancer in adults; and childhood cancer incidence. Limited epidemiological studies were found in the literature that properly address cancer incidence and air pollution in the EMR countries. Outdoor air pollution was not properly addressed in the included studies. Studies showed that using fuel for heating and living near an electricity generator and diesel exhaust exposure were significant contributors to lung cancer. NO2 has been shown to increase the risk of lung and breast cancer incidence. PAHs exposure did not increase the risk of cancer incidence. In conclusion, studies on the link between air pollution and cancer in EMR are limited to few studies in few countries. The reviewed studies have many limitations that make the evidence about the link between air pollution and cancer weak.

Keywords:
air pollution cancer eastern mediterranean region systematic review mortality

Creative CommonsThis work is licensed under a Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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